Parikh Devangi A, Patkar Geeta A, Ganvir Mayur S, Sawant Ajit, Tendolkar Bharati A
Department of Anaesthesiology, Lokmanya Tilak Municipal General Hospital, Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India.
Department of Urology, Lokmanya Tilak Municipal General Hospital, Lokmanya Tilak Municipal Medical College, Mumbai, Maharashtra, India.
Indian J Anaesth. 2017 Apr;61(4):308-314. doi: 10.4103/0019-5049.204247.
Neuraxial anaesthesia has recently become popular for percutaneous nephrolithotomy (PCNL). We conducted a study comparing general anaesthesia (GA) with segmental (T-T) epidural anaesthesia (SEA) for PCNL with respect to anaesthesia and surgical characteristics.
Ninety American Society of Anesthesiologists Physical Status-I and II patients undergoing PCNL randomly received either GA or SEA. Overall patient satisfaction was the primary end point. Intraoperative haemodynamics, epidural block characteristics, post-operative pain, time to rescue analgesic, total analgesic consumption, discharge times from post-anaesthesia care unit, surgeon satisfaction scores and stone clearance were secondary end points. Parametric data were analysed by Student's -test while non-parametric data were compared with Mann-Whitney U-test.
Group SEA reported better patient satisfaction ( = 0.005). Patients in group GA had significantly higher heart rates ( = 0.0001) and comparable mean arterial pressures ( = 0.24). Postoperatively, time to first rescue analgesic and total tramadol consumption was higher in Group GA ( = 0.001). Group SEA had lower pain scores ( = 0.001). Time to reach Aldrete's score of 9 was shorter in group SEA ( = 0.0001). The incidence of nausea was higher in group GA ( = 0.001); vomiting rates were comparable ( = 0.15). One patient in group SEA developed bradycardia which was successfully treated. Eight patients (18%) had hypertensive episodes in group GA versus none in group SEA ( = 0.0001). One patient in GA group had pleural injury and was managed with intercostal drain. Stone clearance and post-operative haemoglobin levels were comparable in both groups.
PCNL under SEA has a role in selected patients, for short duration surgery and in expert hands.
近年来,神经轴索麻醉在经皮肾镜取石术(PCNL)中逐渐流行。我们开展了一项研究,比较全身麻醉(GA)与节段性(T - T)硬膜外麻醉(SEA)用于PCNL时的麻醉和手术相关特征。
90例美国麻醉医师协会身体状况分级为Ⅰ级和Ⅱ级且接受PCNL的患者被随机分为接受GA或SEA两组。总体患者满意度是主要终点。术中血流动力学、硬膜外阻滞特征、术后疼痛、补救性镇痛时间、总镇痛药物消耗量、麻醉后恢复室出院时间、外科医生满意度评分以及结石清除率为次要终点。参数数据采用学生t检验分析,非参数数据采用曼 - 惠特尼U检验进行比较。
SEA组患者满意度更高(P = 0.005)。GA组患者心率显著更高(P = 0.0001),平均动脉压相当(P = 0.24)。术后,GA组首次补救性镇痛时间和曲马多总消耗量更高(P = 0.001)。SEA组疼痛评分更低(P = 0.001)。SEA组达到Aldrete评分为9分的时间更短(P = 0.0001)。GA组恶心发生率更高(P = 0.001);呕吐发生率相当(P = 0.15)。SEA组有1例患者发生心动过缓,经成功治疗。GA组有8例患者(18%)出现高血压发作,而SEA组无(P = 0.0001)。GA组有1例患者发生胸膜损伤,通过肋间引流进行处理。两组结石清除率和术后血红蛋白水平相当。
在特定患者中,由经验丰富的医生实施的短时长手术,SEA用于PCNL有其优势。