Tolou-Ghamari Zahra, Shygannejad Vahid, Ashtari Fereshteh, Chitsaz Ahmad, Palizban Abbas Ali
Isfahan Neurosciences Research Centre, Alzahra Hospital, Isfahan, Iran.
Isfahan Neurosciences Research Centre, Alzahra Hospital, Isfahan, Iran ; Department of Neurology, Isfahan University of Medical Sciences, Isfahan, Iran.
Adv Biomed Res. 2015 Aug 10;4:166. doi: 10.4103/2277-9175.162543. eCollection 2015.
Previous publications reported that an individual's month of birth (MOB) might have an important correlation to that consequent risk of multiple sclerosis (MS).
The aim of this preliminary study was to investigate the distribution of different MOBs inpatients with MS in Isfahan, Iran.
This investigation was conducted to the Isfahan Neurosciences Research Centre. 1283 patients with MS were studied. Clinical data were recorded in d-Base and analyzed using SPSS (version 18) for Windows.
Of the total population studied there were 979 females and 304 males. The mean age of all the patients was 34.6 years (range 10-87 years). Within the total population, the MOBs in the 62% of patients were in the season's spring and summer, and in 38% of patients they were in the season's autumn and winter. As the MOB might be recognized to have a bearing on an individual's risk of contracting MS, the highest and lowest correlations seem to be linked with April, September, May (↑), and November (↓), respectively.
The seasonal relationship between MOBs and MS risk might be pointed toward a potential function for vitamin D throughout pregnancy or the early life of the newborn. Further studies are needed to confirm these correlations.
先前的出版物报道,一个人的出生月份(MOB)可能与随后患多发性硬化症(MS)的风险有重要关联。
这项初步研究的目的是调查伊朗伊斯法罕MS患者中不同出生月份的分布情况。
该调查在伊斯法罕神经科学研究中心进行。研究了1283例MS患者。临床数据记录在d-Base中,并使用适用于Windows的SPSS(版本18)进行分析。
在所有研究对象中,有979名女性和304名男性。所有患者的平均年龄为34.6岁(范围10 - 87岁)。在总人群中,62%患者的出生月份在春季和夏季,38%患者的出生月份在秋季和冬季。由于出生月份可能被认为与个体患MS的风险有关,最高和最低相关性似乎分别与4月、9月、5月(上升)和11月(下降)相关。
出生月份与MS风险之间的季节性关系可能表明维生素D在整个孕期或新生儿早期生活中具有潜在作用。需要进一步研究来证实这些相关性。