Ganzel T M, Brohm J, Nechtman C M, Ganzel B L, Klein J B, Gray L A
Division of Otolaryngology, University of Louisville, School of Medicine, KY 40292.
Laryngoscope. 1989 Feb;99(2):158-61. doi: 10.1288/00005537-198902000-00007.
Cardiac transplantation is now a well-accepted treatment for selected patients who have end-stage heart disease. Of the 38 patients who underwent cardiac transplants at our center from August 1984 through August 1987, 27 received consultation for otolaryngologic problems. Eleven patients had sinonasal complications; 8 had laryngotracheal complications; 4 had otologic complications; 2 had oropharyngeal complications; and 2 had a combination of more than one of the above complications. Of these otolaryngologic disorders, 63% were infectious in etiology. Development of otolaryngologic infections generally did not correlate with either higher doses of maintenance immunosuppression or with treatment of an acute rejection episode, which requires increased immunosuppression. Otolaryngologists should be aware of the sinonasal, laryngotracheal, oropharyngeal, and otologic disorders that can occur in cardiac transplant patients.
心脏移植目前是治疗特定终末期心脏病患者的一种广泛认可的疗法。1984年8月至1987年8月期间,在我们中心接受心脏移植的38例患者中,有27例就耳鼻喉科问题接受了会诊。11例患者出现鼻窦并发症;8例出现喉气管并发症;4例出现耳部并发症;2例出现口咽并发症;2例出现上述多种并发症的组合。在这些耳鼻喉科疾病中,63%的病因是感染性的。耳鼻喉科感染的发生通常与维持性免疫抑制的较高剂量或急性排斥反应的治疗(这需要增加免疫抑制)均无关联。耳鼻喉科医生应了解心脏移植患者可能出现的鼻窦、喉气管、口咽和耳部疾病。