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Cis-interactions between Notch and its ligands block ligand-independent Notch activity.
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Sphingosine-1-phosphate promotes expansion of cancer stem cells via S1PR3 by a ligand-independent Notch activation.
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Endocytic pathways downregulate the L1-type cell adhesion molecule neuroglian to promote dendrite pruning in Drosophila.
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Compensatory flux changes within an endocytic trafficking network maintain thermal robustness of Notch signaling.
Cell. 2014 May 22;157(5):1160-74. doi: 10.1016/j.cell.2014.03.050.
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ESCRT-0 is not required for ectopic Notch activation and tumor suppression in Drosophila.
PLoS One. 2014 Apr 9;9(4):e93987. doi: 10.1371/journal.pone.0093987. eCollection 2014.
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Basal body proteins regulate Notch signaling through endosomal trafficking.
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Loss- and gain-of-function analyses of vacuolar protein sorting 2 in Notch signaling of Drosophila melanogaster.
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