Gómez Ingrid T, Llerena Claudia R, Zabaleta Angie P
Instituto Nacional de Salud, Bogotá, Colombia.
Rev Salud Publica (Bogota). 2015 Jan-Feb;17(1):97-105.
To characterize tuberculosis drug-resistance using anti-tuberculosis drug-sensitivity tests in Colombian prisoners.
Descriptive-retrospective analyses were performed on cases of tuberculosis in prisoners. Samples were evaluated by the National Reference Laboratory. Conditions like gender, TB/VIH co-infection and drug-resistance were evaluated.
Anti-tuberculosis drug-sensitivity tests were carried out on 72 prisoners. Results showed a distribution of 90.7 % of cases in males and 9.3 % of cases in females. 12 % of cases were TB/VIH co-infections, 94 % of the cases had not received any anti-tuberculosis treatment before, six isolates were drug-resistant corresponding to 8.8 % of total cases, and two cases were multi drug-resistant representing 1.3 % of the cases. Of the drug-resistant cases, 83.3 % were TB/VIH co-infected. Previously treated cases corresponded to 5.6 % of the total cases analyzed. One case with TB/VIH co-infection and rifampicin resistance was observed, representing 1.3 % of the total cases.
The government must create a clear policy for prisoners in Colombia, because a high rate of disease in prisoners was observed. In addition, the results showed an association between drug-resistance and TB/VIH co-infection. Overcrowding and low quality of life in penitentiaries could become an important public health problem.
通过对哥伦比亚囚犯进行抗结核药物敏感性试验来描述结核病耐药情况。
对囚犯中的结核病病例进行描述性回顾分析。样本由国家参考实验室进行评估。对性别、结核病/艾滋病毒合并感染及耐药性等情况进行评估。
对72名囚犯进行了抗结核药物敏感性试验。结果显示，病例分布为男性占90.7%，女性占9.3%。12%的病例为结核病/艾滋病毒合并感染，94%的病例此前未接受过任何抗结核治疗，6株菌株耐药，占总病例的8.8%，2例为多重耐药，占病例的1.3%。在耐药病例中，83.3%为结核病/艾滋病毒合并感染。此前接受过治疗的病例占所分析总病例的5.6%。观察到1例结核病/艾滋病毒合并感染且对利福平耐药的病例，占总病例的1.3%。
政府必须为哥伦比亚的囚犯制定明确政策，因为观察到囚犯中的疾病发生率很高。此外，结果显示耐药性与结核病/艾滋病毒合并感染之间存在关联。监狱过度拥挤和生活质量低下可能成为一个重要的公共卫生问题。
