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采用覆膜支架治疗椎动脉感染性动脉瘤:病例报告

An Infected Aneurysm of the Vertebral Artery Treated with a Stent-graft: A Case Report.

作者信息

Hashimoto Kenji, Isaka Fumiaki, Yamashita Kohsuke

机构信息

Department of Neurosurgery, Kishiwada City Hospital.

出版信息

Neurol Med Chir (Tokyo). 2015;55(11):852-5. doi: 10.2176/nmc.cr.2015-0046. Epub 2015 Oct 6.

Abstract

In a 75-year-old man, a growing vertebral artery aneurysm at the C3/4 intervertebral level was found at postoperative evaluation of cervical abscess, which was diagnosed as a complication of sepsis subsequent to cholangitis. Even after a successful antibiotic treatment and a surgical drainage, the aneurysm grew enough to cause compression of esophagus and trachea. The aneurysm was judged to be infection-related, based on the clinical course and the anatomical vicinity to the abscess. Following a dual antiplatelet treatment (clopidogrel 75 mg and aspirin 100 mg per day) for a week, the patient underwent endovascular treatment of the aneurysm with a stent-graft. Postoperative angiography showed complete obliteration of the aneurysm with preserving patency of the vertebral artery. A dual antiplatelet treatment was continued for 6 months and was changed to a single antiplatelet treatment (clopidogrel 75 mg per day) thereafter. Neither recurrence of the aneurysm nor stent-graft infection was observed for 4 years of follow-up. This case illustrates the potential use of a stent-graft in the treatment of an infected aneurysm.

摘要

在一名75岁男性患者中,于颈部脓肿术后评估时发现C3/4椎间水平的椎动脉动脉瘤不断增大,该颈部脓肿被诊断为胆管炎继发败血症的并发症。即便在抗生素治疗成功且进行了外科引流之后,动脉瘤仍不断增大,足以压迫食管和气管。基于临床病程以及动脉瘤与脓肿在解剖位置上的邻近关系,判断该动脉瘤与感染相关。在进行了为期一周的双重抗血小板治疗(每日氯吡格雷75毫克和阿司匹林100毫克)后,患者接受了带覆膜支架的动脉瘤血管内治疗。术后血管造影显示动脉瘤完全闭塞,椎动脉保持通畅。双重抗血小板治疗持续了6个月,之后改为单一抗血小板治疗(每日氯吡格雷75毫克)。在4年的随访中,未观察到动脉瘤复发或带覆膜支架感染的情况。该病例说明了带覆膜支架在治疗感染性动脉瘤方面的潜在应用。

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