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轻微头部外伤后伴有良性扁桃体异位的扁桃体挫伤。

Tonsillar contusion associated with benign tonsillar ectopia following minor head trauma.

作者信息

Serlin Yonatan, Benifla Mony, Shelef Ilan

机构信息

The Laboratory for Experimental Neurosurgery, Department of Physiology and Cell Biology, Zlotowski Center for Neuroscience, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, 8410501, Israel.

Department of Neurosurgery, Hadassah-Hebrew University Medical Center, P.O. Box 12000, Jerusalem, 91120, Israel.

出版信息

Childs Nerv Syst. 2016 May;32(5):881-5. doi: 10.1007/s00381-015-2924-y. Epub 2015 Oct 5.

DOI:10.1007/s00381-015-2924-y
PMID:26438549
Abstract

PURPOSE

The relationship between tonsil position and symptomatic cerebellar contusion is unclear. To date, there are no reports of symptomatic traumatic brain injury associated with benign tonsillar ectopia. Reported cases are limited to prominent cerebellar tonsillar displacement by ≥5 mm (i.e., Chiari malformations).

METHODS

The authors describe a case of symptomatic concussion in a toddler with unusual computerized tomography (CT) presentation and incidental finding of benign tonsillar ectopia, hemorrhagic contusion of the tonsils, blood-brain barrier (BBB) disruption and delayed atrophy shown using magnetic resonance imaging (MRI) studies. The radiological presentation and the clinical challenges are discussed through a review of the literature.

CONCLUSION

This case suggests that damage to cerebellar structures is not limited only to overt tonsillar herniation. Benign tonsillar ectopia may predispose to cerebellar contusion even after minor concussion and thus has a clinical significance. The current paradigm viewing only noticeable tonsillar herniation as a risk factor for hindbrain injury should be revisited.

摘要

目的

扁桃体位置与有症状的小脑挫伤之间的关系尚不清楚。迄今为止,尚无关于与良性扁桃体异位相关的有症状创伤性脑损伤的报道。已报道的病例仅限于小脑扁桃体明显移位≥5毫米(即Chiari畸形)。

方法

作者描述了一例幼儿有症状性脑震荡的病例,其计算机断层扫描(CT)表现异常,并偶然发现良性扁桃体异位、扁桃体出血性挫伤、血脑屏障(BBB)破坏以及磁共振成像(MRI)研究显示的延迟性萎缩。通过文献回顾讨论了放射学表现和临床挑战。

结论

该病例表明,小脑结构的损伤不仅限于明显的扁桃体疝。即使在轻度脑震荡后,良性扁桃体异位也可能易导致小脑挫伤,因此具有临床意义。应重新审视目前仅将明显的扁桃体疝视为后脑损伤危险因素的范式。

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引用本文的文献

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Childs Nerv Syst. 2025 Mar 19;41(1):135. doi: 10.1007/s00381-025-06795-4.
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Tonsillar herniation spectrum: more than just Chiari I. Update and controversies on classification and management.扁桃体疝谱:不仅仅是 Chiari I 型。分类和管理的更新与争议。
Neurosurg Rev. 2020 Dec;43(6):1473-1492. doi: 10.1007/s10143-019-01198-x. Epub 2019 Nov 10.
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Complete early regression of asymptomatic hindbrain herniation caused by minor head trauma.

本文引用的文献

1
Review Article: Chiari Type I Malformation with or Without Syringomyelia: Prevalence and Genetics.综述文章:伴或不伴脊髓空洞症的Chiari I型畸形:患病率与遗传学
J Genet Couns. 2003 Aug;12(4):297-311. doi: 10.1023/A:1023948921381.
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Imaging blood-brain barrier dysfunction in football players.足球运动员血脑屏障功能障碍的影像学研究
JAMA Neurol. 2014 Nov;71(11):1453-5. doi: 10.1001/jamaneurol.2014.2682.
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The Chiari malformations: a review with emphasis on anatomical traits.Chiari畸形:一篇着重于解剖学特征的综述
Oxf Med Case Reports. 2019 Feb 25;2019(2):omz002. doi: 10.1093/omcr/omz002. eCollection 2019 Feb.
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Traumatic Transient Herniation Concomitant with Tonsillar Hemorrhagic Contusion in a Child.儿童创伤性短暂性疝伴扁桃体出血性挫伤
Open Access Maced J Med Sci. 2017 Oct 6;5(6):771-773. doi: 10.3889/oamjms.2017.167. eCollection 2017 Oct 15.
Clin Anat. 2015 Mar;28(2):184-94. doi: 10.1002/ca.22442. Epub 2014 Jul 25.
4
Distribution of cerebellar tonsil position: implications for understanding Chiari malformation.小脑扁桃体位置的分布:对理解 Chiari 畸形的意义。
J Neurosurg. 2013 Sep;119(3):812-9. doi: 10.3171/2013.5.JNS121825. Epub 2013 Jun 14.
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Incidence of cerebellar tonsillar ectopia in idiopathic intracranial hypertension: a mimic of the Chiari I malformation.特发性颅内高压中小脑扁桃体异位的发生率:Chiari I 畸形的一种类似表现。
AJNR Am J Neuroradiol. 2012 Nov;33(10):1901-6. doi: 10.3174/ajnr.A3068. Epub 2012 Jun 21.
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Acute deterioration of a Chiari I malformation: an uncommon neurosurgical emergency.Chiari I 畸形的急性恶化:一种罕见的神经外科急症。
Childs Nerv Syst. 2011 Jun;27(6):857-60. doi: 10.1007/s00381-011-1442-9. Epub 2011 Apr 7.
7
Blood-brain barrier breakdown following traumatic brain injury: a possible role in posttraumatic epilepsy.创伤性脑损伤后血脑屏障破坏:在创伤后癫痫中可能发挥的作用
Cardiovasc Psychiatry Neurol. 2011;2011:765923. doi: 10.1155/2011/765923. Epub 2011 Feb 22.
8
Endoscopic third ventriculostomy for the management of Chiari I and related hydrocephalus: outcome and pathogenetic implications.内镜第三脑室造瘘术治疗 Chiari I 畸形和相关脑积水:结果和发病机制的影响。
Neurosurgery. 2011 Apr;68(4):950-6. doi: 10.1227/NEU.0b013e318208f1f3.
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Blood-brain barrier breakdown as a therapeutic target in traumatic brain injury.血脑屏障破坏作为创伤性脑损伤的治疗靶点。
Nat Rev Neurol. 2010 Jul;6(7):393-403. doi: 10.1038/nrneurol.2010.74. Epub 2010 Jun 15.
10
Shunt malfunction causing acute neurological deterioration in 2 patients with previously asymptomatic Chiari malformation Type I. Report of two cases.分流功能障碍导致2例既往无症状的Ⅰ型Chiari畸形患者出现急性神经功能恶化。两例报告。
J Neurosurg Pediatr. 2009 Aug;4(2):170-5. doi: 10.3171/2009.4.PEDS0936.