Tubbs R Shane, Wellons John C, Oakes W Jerry
Department of Cell Biology, University of Alabama at Birmingham, Birmingham, Ala. 35233, USA.
Pediatr Neurosurg. 2002 Oct;37(4):199-202. doi: 10.1159/000065399.
There has been almost no evaluation or discussion of the symmetry of tonsillar ectopia in the medical literature. We measured the degree of left and right tonsillar herniation in 42 pediatric patients with a symptomatic Chiari I malformation and made clinical/radiological correlations. 18% of all patients with tonsillar asymmetry had clinical symptoms or physical findings referable to the inequality of their hindbrain herniation. In addition, 95% of patients with a coexisting syringomyelia had a right cerebellar tonsillar herniation greater than the left. We hypothesize that slight differences in posterior cranial fossa morphology may physically allow for greater unilateral herniation of the left or right cerebellar tonsil, which may be manifested in a patient's clinical presentation.
医学文献中几乎没有对扁桃体异位对称性的评估或讨论。我们测量了42例有症状的Chiari I型畸形儿科患者左右扁桃体疝出的程度，并进行了临床/放射学相关性分析。所有扁桃体不对称的患者中，18%有可归因于其后脑疝出不平等的临床症状或体格检查发现。此外，95%并存脊髓空洞症的患者右侧小脑扁桃体疝出大于左侧。我们推测后颅窝形态的细微差异可能在生理上允许左或右小脑扁桃体更大程度的单侧疝出，这可能在患者的临床表现中体现出来。
