Sundbøll Jens, Hansson Nils Henrik Stubkjær, Baerentzen Steen, Pareek Manan
Department of Cardiology, Aarhus University Hospital, Aarhus N, Denmark.
Department of Pathology, Aarhus University Hospital, Aarhus C, Denmark.
BMJ Case Rep. 2015 Oct 5;2015:bcr2015212178. doi: 10.1136/bcr-2015-212178.
A 64-year-old previously healthy woman consulted her general practitioner because of recurrent episodes of right-sided monocular transient visual loss (ie, amaurosis fugax). At first, these symptoms were followed over time, but as the attacks worsened, and were accompanied by dizziness and general discomfort, the patient was admitted to the department of neurology for further investigations. CT of the brain was normal; however, during admission, the patient developed rapid atrial fibrillation and was transferred to the department of cardiology. Transthoracic echocardiography revealed a massive tumour on the atrial side of the anterior mitral valve leaflet, partly obstructing the mitral valve inflow. The tumour was excised and a biological prosthetic mitral valve inserted. The tumour was histologically determined to be a highly malignant dedifferentiated chondrosarcoma. After 6 months, the tumour relapsed and expanded aggressively to completely obstruct the mitral valve inflow, ultimately leading to cardiac arrest and death.
一名64岁既往健康的女性因右侧单眼短暂性视力丧失（即一过性黑矇）反复发作而咨询其全科医生。起初，这些症状随时间进行观察，但随着发作加重，并伴有头晕和全身不适，患者被收入神经内科作进一步检查。脑部CT正常；然而，住院期间，患者出现快速心房颤动并被转至心内科。经胸超声心动图显示二尖瓣前叶心房侧有一个巨大肿瘤，部分阻塞二尖瓣血流。肿瘤被切除并植入生物人工二尖瓣。肿瘤经组织学确定为高度恶性的去分化软骨肉瘤。6个月后，肿瘤复发并迅速扩展，完全阻塞二尖瓣血流，最终导致心脏骤停和死亡。
