Gallagher I H, Cutress T W
Community Dent Oral Epidemiol. 1977 Jan;5(1):1-6. doi: 10.1111/j.1600-0528.1977.tb01610.x.
A dental gel containing 1 % chlorhexidine was applied daily to the teeth of mentally retarded patients for a period of 6 months. Although possible antimicrobial effects were noted, the gel had no practical value in reducing the numbers of different plaque bacteria. It is suggested that the lack of effect may be due to changes in susceptibility of the oral flora surviving in the mouth, allowing subsequent recolonization of the teeth.
一种含1%洗必泰的牙科凝胶每天用于智障患者的牙齿，持续6个月。尽管观察到了可能的抗菌效果，但该凝胶在减少不同菌斑细菌数量方面没有实际价值。有人认为，缺乏效果可能是由于口腔中存活的口腔菌群敏感性发生变化，使得牙齿随后再次被定植。
