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A Randomized Trial Comparing Stapled Rectal Mucosectomy Versus Open and Semiclosed Hemorrhoidectomy.

作者信息

Ripetti Valter, La Vaccara Vincenzo, Greco Santi, Arullani Augusto

机构信息

Department of General Surgery, Campus Bio-Medico University, Rome, Italy.

出版信息

Dis Colon Rectum. 2015 Nov;58(11):1083-90. doi: 10.1097/DCR.0000000000000454.

DOI:10.1097/DCR.0000000000000454
PMID:26445182
Abstract

BACKGROUND

Different results have been reported concerning the postoperative outcomes of different surgical approaches for hemorrhoids.

OBJECTIVE

We aimed to determine the postoperative outcome following 3 main surgical techniques.

DESIGN

A prospective, randomized trial was designed with 180 patients in 3 arms of 60 patients each.

SETTINGS

The study was conducted from April 1999 to January 2007 at the University Hospital "Campus Bio-Medico di Roma."

PATIENTS

All of the patients who were referred for hemorrhoid surgery were enrolled according to inclusion and exclusion criteria (ISRCTN12040297).

INTERVENTIONS

Treatments according to the open, semiclosed, and stapled techniques were compared.

MAIN OUTCOME MEASURES

Sample size was calculated to determine a difference in terms of the intensity of postoperative pain at the first week and the days required for return to work activity.

RESULTS

After 1 week, patients who underwent semiclosed hemorrhoidectomy reported significantly less pain (p < 0.01) and a significant decrease in analgesic intake from the third postoperative day (p < 0.01) than after the other 2 techniques. The patients resumed work ≈11 days after semiclosed and stapled techniques (11.8 and 11.6 days), which was earlier compared with 21.3 days in the open group (p < 0.05).

LIMITATIONS

The high number of patients excluded might be considered a limitation of the study, but our selection criteria including patients living within 50 km of the hospital allowed for a low rate (9.4%) of patients lost to follow-up.

CONCLUSIONS

This study found an earlier resumption of work and less pain in patients who underwent the stapled and semiclosed procedures rather than open, which was associated with more complications, particularly because of a higher rate of stenosis (see Video, Supplemental Digital Content 1, http://links.lww.com/DCR/A196).

摘要

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