CT结果不充分时，动态对比增强MRI与PET/CT在喉癌评估中的比较
Comparison of Dynamic Contrast-Enhanced MRI and PET/CT in the Evaluation of Laryngeal Cancer After Inadequate CT Results.
作者信息
Citil Serdal, Dogan Serap, Atilgan Hasan Ikbal, Menzilcioglu Mehmet Sait, Sahin Tuna, Abdulrezzak Ummuhan, Duymus Mahmut, Ozturk Mustafa
机构信息
Division of Radiology, Ministry of Health Kahramanmaras Necip Fazıl City Hospital, Kahramanmaras, Turkey.
Department of Radiology, Erciyes University Hospital, Kayseri, Turkey.
出版信息
Pol J Radiol. 2015 Sep 13;80:428-32. doi: 10.12659/PJR.895041. eCollection 2015.
BACKGROUND
To investigate the diagnostic value of dynamic magnetic resonance imaging (MRI) and positron emission tomography/computed tomography (PET/CT) for laryngeal cancers after inadequate CT results.
MATERIAL/METHODS: The study comprised 45 patients investigated for primary laryngeal cancer or recurrence-residue in which CT was considered inadequate. A mass was found in 20 patients. Dynamic MRI and PET/CT were compared for diagnosis of mass, lymph node involvement, recurrence and residue. The dynamic curves formed in dynamic MRI were investigated for diagnostic contributions.
RESULTS
The sensitivity and specificity of the dynamic MRI, for supraglottic, glottic and subglottic location, was 100%, 80%, and 92%; 100%, 85%, and 100%, respectively. In PET/CT the sensitivity and specificity were 100% for all of those localizations. For lymph node involvement, the sensitivity of dynamic MRI and PET/CT was 100%, the specificity was 100% and 93%, respectively. For recurrence-residue, the sensitivity and specificity of dynamic MRI were 86% and 67%, respectively, with 100% sensitivity and specificity in PET/CT. The sensitivity of type A curve for detection of malignancy was 40%, and specificity was 100%. When type A and B curves were included, the sensitivity was 100%.
CONCLUSIONS
For patients investigated for laryngeal cancer in which CT is considered inadequate, dynamic MRI or PET/CT is useful.
背景
探讨在CT检查结果不充分的情况下，动态磁共振成像（MRI）和正电子发射断层扫描/计算机断层扫描（PET/CT）对喉癌的诊断价值。
材料/方法：本研究纳入了45例因原发性喉癌或复发残留而接受检查的患者，这些患者的CT检查结果被认为不充分。20例患者发现有肿物。比较动态MRI和PET/CT在肿物、淋巴结受累、复发和残留诊断方面的表现。研究动态MRI形成的动态曲线的诊断价值。
结果
动态MRI对声门上型、声门型和声门下型肿物的敏感性和特异性分别为100%、80%和92%；以及100%、85%和100%。在PET/CT中，所有这些部位的敏感性和特异性均为100%。对于淋巴结受累，动态MRI和PET/CT的敏感性均为100%，特异性分别为100%和93%。对于复发残留，动态MRI的敏感性和特异性分别为86%和67%，PET/CT的敏感性和特异性均为100%。A型曲线检测恶性肿瘤的敏感性为40%，特异性为100%。当纳入A型和B型曲线时，敏感性为100%。
结论
对于CT检查结果不充分的喉癌患者，动态MRI或PET/CT是有用的。
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