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标杆管理对2型糖尿病护理质量的影响:希腊OPTIMISE(包括标杆管理和标准治疗的2型糖尿病优化管理)研究结果

Effects of benchmarking on the quality of type 2 diabetes care: results of the OPTIMISE (Optimal Type 2 Diabetes Management Including Benchmarking and Standard Treatment) study in Greece.

作者信息

Tsimihodimos Vasilis, Kostapanos Michael S, Moulis Alexandros, Nikas Nikos, Elisaf Moses S

机构信息

Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece.

Medical Department, AstraZeneca SA, Athens, Greece.

出版信息

Ther Adv Endocrinol Metab. 2015 Oct;6(5):199-209. doi: 10.1177/2042018815592803.

Abstract

OBJECTIVES

To investigate the effect of benchmarking on the quality of type 2 diabetes (T2DM) care in Greece.

METHODS

The OPTIMISE (Optimal Type 2 Diabetes Management Including Benchmarking and Standard Treatment) study [ClinicalTrials.gov identifier: NCT00681850] was an international multicenter, prospective cohort study. It included physicians randomized 3:1 to either receive benchmarking for glycated hemoglobin (HbA1c), systolic blood pressure (SBP) and low-density lipoprotein cholesterol (LDL-C) treatment targets (benchmarking group) or not (control group). The proportions of patients achieving the targets of the above-mentioned parameters were compared between groups after 12 months of treatment. Also, the proportions of patients achieving those targets at 12 months were compared with baseline in the benchmarking group.

RESULTS

In the Greek region, the OPTIMISE study included 797 adults with T2DM (570 in the benchmarking group). At month 12 the proportion of patients within the predefined targets for SBP and LDL-C was greater in the benchmarking compared with the control group (50.6 versus 35.8%, and 45.3 versus 36.1%, respectively). However, these differences were not statistically significant. No difference between groups was noted in the percentage of patients achieving the predefined target for HbA1c. At month 12 the increase in the percentage of patients achieving all three targets was greater in the benchmarking (5.9-15.0%) than in the control group (2.7-8.1%). In the benchmarking group more patients were on target regarding SBP (50.6% versus 29.8%), LDL-C (45.3% versus 31.3%) and HbA1c (63.8% versus 51.2%) at 12 months compared with baseline (p < 0.001 for all comparisons).

CONCLUSION

Benchmarking may comprise a promising tool for improving the quality of T2DM care. Nevertheless, target achievement rates of each, and of all three, quality indicators were suboptimal, indicating there are still unmet needs in the management of T2DM.

摘要

目的

研究对标管理对希腊2型糖尿病(T2DM)护理质量的影响。

方法

OPTIMISE(包括对标管理和标准治疗的2型糖尿病优化管理)研究[ClinicalTrials.gov标识符:NCT00681850]是一项国际多中心前瞻性队列研究。该研究将医生按3:1随机分组,分别接受糖化血红蛋白(HbA1c)、收缩压(SBP)和低密度脂蛋白胆固醇(LDL-C)治疗目标的对标管理(对标管理组)或不接受对标管理(对照组)。治疗12个月后,比较两组中达到上述参数目标的患者比例。此外,还将对标管理组中12个月时达到这些目标的患者比例与基线进行比较。

结果

在希腊地区,OPTIMISE研究纳入了797例成年T2DM患者(对标管理组570例)。在第12个月时,对标管理组中达到SBP和LDL-C预定义目标的患者比例高于对照组(分别为50.6%对35.8%,45.3%对36.1%)。然而,这些差异无统计学意义。两组中达到HbA1c预定义目标的患者百分比无差异。在第12个月时,对标管理组中达到所有三个目标的患者百分比增幅(5.9 - 15.0%)大于对照组(2.7 - 8.1%)。与基线相比,对标管理组在第12个月时更多患者在SBP(50.6%对29.8%)、LDL-C(45.3%对31.3%)和HbA1c(63.8%对51.2%)方面达到目标(所有比较p < 0.001)。

结论

对标管理可能是提高T2DM护理质量的一个有前景的工具。然而,每个质量指标以及所有三个质量指标的目标达成率都未达到最佳,表明在T2DM管理中仍存在未满足的需求。

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