Paltiel H J, Lebowitz R L
Department of Radiology, Children's Hospital, Boston, MA 02115.
Radiology. 1989 Mar;170(3 Pt 1):787-9. doi: 10.1148/radiology.170.3.2644663.
The records were reviewed of the 25 neonates found to have hydronephrosis due to primary vesicoureteral reflux at the authors' hospital in the 6 1/2-year period from January 1981 to June 1987. Modes of discovery and investigation, detection of associated lesions, treatment, and errors in both diagnosis and management were evaluated. Twenty-one of the neonates were boys. Fourteen cases were found at fetal screening, and the infants were asymptomatic. Inappropriate maternal/fetal intervention occurred in four cases: Three were incorrectly thought to have posterior urethral valves. The increased number of neonates found to have reflux is attributable to the widespread availability of obstetric ultrasonography and early screening of infants at risk for urinary tract abnormalities. Since the pathophysiologic characteristics of reflux are well understood, appropriate postnatal therapy can be instituted without delay.
回顾了1981年1月至1987年6年半期间作者所在医院发现的25例因原发性膀胱输尿管反流导致肾积水的新生儿病例记录。评估了发现和检查方式、相关病变的检测、治疗以及诊断和管理中的失误。其中21例新生儿为男性。14例在胎儿筛查时被发现,婴儿无症状。4例发生了不适当的母婴干预:3例被错误地认为患有后尿道瓣膜。发现反流的新生儿数量增加归因于产科超声检查的广泛应用以及对有尿路异常风险婴儿的早期筛查。由于反流的病理生理特征已得到充分了解,因此可以立即进行适当的产后治疗。