足月儿母乳喂养中铁的概述
An Overview of Iron in Term Breast-Fed Infants.
作者信息
Qasem Wafaa A, Friel James K
机构信息
Department of Human Nutritional Sciences, Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, Winnipeg, MB, Canada.
出版信息
Clin Med Insights Pediatr. 2015 Sep 23;9:79-84. doi: 10.4137/CMPed.S26572. eCollection 2015.
Abstract
BACKGROUND
Iron is an essential nutrient for normal growth and neurodevelopment of infants. Iron deficiency (ID) remains the most common micronutrient deficiency worldwide. There are convincing data that ID is associated with negative effects on neurological and psychomotor development.
OBJECTIVES
In this review, we provide an overview of current knowledge of the importance of iron in normal term breast-fed infants with a focus on recommendations, metabolism, and iron requirements.
CONCLUSIONS
Health organizations around the world recommend the introduction of iron-rich foods or iron supplements for growing infants to prevent ID. However, there is no routine screening for ID in infancy. Multicenter trials with long-term follow-up are needed to investigate the association between iron fortification/supplementation and various health outcomes.
摘要
背景
铁是婴儿正常生长和神经发育所必需的营养素。缺铁仍然是全球最常见的微量营养素缺乏症。有确凿的数据表明，缺铁与对神经和精神运动发育的负面影响有关。
目的
在本综述中，我们概述了铁在足月母乳喂养婴儿中的重要性的当前知识，重点是建议、代谢和铁需求。
结论
世界各地的卫生组织建议为成长中的婴儿引入富含铁的食物或铁补充剂以预防缺铁。然而，婴儿期没有对缺铁进行常规筛查。需要进行长期随访的多中心试验来研究铁强化/补充与各种健康结果之间的关联。
相似文献
1
An Overview of Iron in Term Breast-Fed Infants.足月儿母乳喂养中铁的概述
Clin Med Insights Pediatr. 2015 Sep 23;9:79-84. doi: 10.4137/CMPed.S26572. eCollection 2015.
2
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区，服用抗叶酸抗疟药物的人群中，叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
3
Iron requirements in infancy.婴儿期的铁需求。
Ann Nutr Metab. 2011;59(1):59-63. doi: 10.1159/000332138. Epub 2011 Nov 25.
4
Multiple micronutrient powders for home (point-of-use) fortification of foods in pregnant women.用于孕妇家庭（使用点）食品强化的多种微量营养素粉。
Cochrane Database Syst Rev. 2015 Jun 19;2015(6):CD011158. doi: 10.1002/14651858.CD011158.pub2.
5
Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age (Review).使用多种微量营养素粉对两岁以下儿童的食物进行家庭强化以促进健康和营养（综述）
Evid Based Child Health. 2013 Jan;8(1):112-201. doi: 10.1002/ebch.1895.
6
Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age.采用多种微量营养素粉对两岁以下儿童的食物进行家庭强化以促进健康与营养
Cochrane Database Syst Rev. 2011 Sep 7(9):CD008959. doi: 10.1002/14651858.CD008959.pub2.
7
Home fortification of foods with multiple micronutrient powders for health and nutrition in children under two years of age.使用多种微量营养素粉对两岁以下儿童的食品进行家庭强化以促进健康和营养。
Cochrane Database Syst Rev. 2020 Feb 28;2(2):CD008959. doi: 10.1002/14651858.CD008959.pub3.
8
Iron requirements of infants and toddlers.婴幼儿的铁需求。
J Pediatr Gastroenterol Nutr. 2014 Jan;58(1):119-29. doi: 10.1097/MPG.0000000000000206.
9
Health outcomes of iron supplementation and/or food fortification in iron-replete children aged 4-24 months: protocol for a systematic review and meta-analysis.铁补充剂和/或食物强化对 4-24 个月铁充足儿童健康结局的影响：系统评价和荟萃分析方案。
Syst Rev. 2019 Nov 1;8(1):253. doi: 10.1186/s13643-019-1185-3.
10
Iron deficiency in infancy: current insights.婴儿缺铁：最新见解。
Curr Opin Clin Nutr Metab Care. 2021 May 1;24(3):240-245. doi: 10.1097/MCO.0000000000000749.
引用本文的文献
1
Iron biomarkers in men with infertility are associated with sperm DNA hydroxymethylation and cumulative live birth rates: a prospective study.男性不育症患者的铁生物标志物与精子DNA羟甲基化及累积活产率相关：一项前瞻性研究。
J Transl Med. 2025 Aug 5;23(1):861. doi: 10.1186/s12967-025-06777-9.
2
The Critical Role of Iron in Pregnancy, Puerperium, and Fetal Development.铁在妊娠、产褥期及胎儿发育中的关键作用。
J Clin Med. 2025 May 16;14(10):3482. doi: 10.3390/jcm14103482.
3
Predictors of anemia among infants at the age of one year attending health centers in the West Bank/Palestine: a retrospective study.西岸/巴勒斯坦地区健康中心一岁婴儿贫血的预测因素：一项回顾性研究。
BMC Public Health. 2025 Jan 16;25(1):179. doi: 10.1186/s12889-025-21355-w.
4
Effects of iron deficiency and iron supplementation at the host-microbiota interface: Could a piglet model unravel complexities of the underlying mechanisms?缺铁和补铁在宿主-微生物群界面的影响：仔猪模型能否揭示潜在机制的复杂性？
Front Nutr. 2022 Oct 4;9:927754. doi: 10.3389/fnut.2022.927754. eCollection 2022.
5
Acid-suppressive therapy among infants and risk of anemia at 12 months of age.婴儿期的抑酸治疗与12月龄时的贫血风险
SAGE Open Med. 2022 Sep 8;10:20503121221123117. doi: 10.1177/20503121221123117. eCollection 2022.
6
Iron Status of Infants in the First Year of Life in Northern Taiwan.台湾北部地区婴儿一岁内的铁营养状况。
Nutrients. 2020 Jan 3;12(1):139. doi: 10.3390/nu12010139.
7
Vitamin and Mineral Supplementation Practices in Preterm Infants: A Survey of Australian and New Zealand Neonatal Intensive and Special Care Units.维生素和矿物质补充在早产儿中的应用：对澳大利亚和新西兰新生儿重症监护病房和特殊护理病房的调查。
Nutrients. 2019 Dec 23;12(1):51. doi: 10.3390/nu12010051.
8
Iron and the Breastfed Infant.铁与母乳喂养的婴儿
Antioxidants (Basel). 2018 Apr 6;7(4):54. doi: 10.3390/antiox7040054.
本文引用的文献
1
Screening and routine supplementation for iron deficiency anemia: a systematic review.筛查和常规补充铁缺乏性贫血：系统评价。
Pediatrics. 2015 Apr;135(4):723-33. doi: 10.1542/peds.2014-3979.
2
Iron, anemia and hepcidin in malaria.疟疾中的铁、贫血与铁调素
Front Pharmacol. 2014 May 30;5:125. doi: 10.3389/fphar.2014.00125. eCollection 2014.
3
Iron requirements of infants and toddlers.婴幼儿的铁需求。
J Pediatr Gastroenterol Nutr. 2014 Jan;58(1):119-29. doi: 10.1097/MPG.0000000000000206.
4
Hepcidin decreases over the first year of life in healthy African infants.在健康的非洲婴儿中，铁调素在出生后的第一年里会减少。
Br J Haematol. 2014 Jan;164(1):150-3. doi: 10.1111/bjh.12567. Epub 2013 Sep 20.
5
A review of cord blood concentrations of iron status parameters to define reference ranges for preterm infants.铁状态参数脐带血浓度综述：为早产儿定义参考范围。
Neonatology. 2013;104(3):194-202. doi: 10.1159/000353161. Epub 2013 Aug 28.
6
Effect of timing of umbilical cord clamping of term infants on maternal and neonatal outcomes.足月儿脐带结扎时机对母婴结局的影响。
Cochrane Database Syst Rev. 2013 Jul 11;2013(7):CD004074. doi: 10.1002/14651858.CD004074.pub3.
7
Functional significance of early-life iron deficiency: outcomes at 25 years.早期铁缺乏的功能意义：25 年的结果。
J Pediatr. 2013 Nov;163(5):1260-6. doi: 10.1016/j.jpeds.2013.05.015. Epub 2013 Jul 1.
8
Nutrition for healthy term infants: recommendations from birth to six months.足月健康婴儿的营养：从出生到六个月的建议
Can J Diet Pract Res. 2012 Winter;73(4):204. doi: 10.3148/73.4.2012.204.
9
Breastfeeding and the use of human milk: an analysis of the American Academy of Pediatrics 2012 Breastfeeding Policy Statement.母乳喂养与母乳使用：对美国儿科学会2012年母乳喂养政策声明的分析
Breastfeed Med. 2012 Oct;7(5):323-4. doi: 10.1089/bfm.2012.0067. Epub 2012 Sep 4.
10
Iron.铁
Adv Nutr. 2012 Jul 1;3(4):532-3. doi: 10.3945/an.112.002261.
Zotero 插件