Williams J E, Eisenberg G H, Cavanaugh D C
J Hyg (Lond). 1977 Feb;78(1):27-31. doi: 10.1017/s0022172400055893.
The decline of maternal antibodies to the fraciton I antigen of Yersinia pestis was investigated in newly weaned Rattus norvegicus obtained from dams vaccinated with strain EV76(51F) of Y. pestis. IHA titre decreased by 50% each 7-3 days and CF titre declined 50% each 10-0 days in young rats. An analysis of available data indicated that maternal IHA and CF antibodies could persist to 3 months of age. Therefore, positive serologic reactions in young R. norvegicus, detected in the course of serological surveys, could be the result either of active immunization after exposure to the plague bacillus or of transient passive immunization (i.e. maternal antibody).
对从接种了鼠疫耶尔森氏菌EV76(51F)菌株的母鼠所获新断奶的褐家鼠中鼠疫耶尔森氏菌I抗原的母源抗体衰退情况进行了研究。幼鼠的间接血凝试验（IHA）效价每7 - 3天下降50%，补体结合试验（CF）效价每10 - 0天下降50%。对现有数据的分析表明，母源IHA和CF抗体可持续至3月龄。因此，在血清学调查过程中检测到的幼龄褐家鼠阳性血清学反应，可能是接触鼠疫杆菌后主动免疫的结果，也可能是短暂被动免疫（即母源抗体）的结果。
