Department of Surgical Oncology, Ningbo No. 2 Hospital, Ningbo, China.
Oncol Res Treat. 2015;38(10):528-31. doi: 10.1159/000440690. Epub 2015 Sep 27.
The aim of this study was to compare the complication rates between completion thyroidectomy and primary total thyroidectomy for differentiated thyroid cancer (DTC).
PubMed, the Web of Knowledge, and the China Journal Net were searched for studies concerning the treatment of DTC published in 1990-2014. A meta-analysis was performed to compare the effects of different treatments.
7 studies with a total of 1,208 patients were included. There were no statistically significant differences regarding the presence of temporary recurrent laryngeal nerve (RLN) palsy, permanent RLN palsy, temporary hypocalcemia, permanent hypocalcemia, hematoma, and wound infection.
Completion thyroidectomy can be performed with acceptable morbidity in select cases of DTC who could not be properly diagnosed perioperatively or who recurred after less than total thyroidectomy.
本研究旨在比较分化型甲状腺癌（DTC）患者行甲状腺全切除术与初次甲状腺全切除术的并发症发生率。
检索 1990 年至 2014 年发表的有关 DTC 治疗的文献，检索数据库包括 PubMed、Web of Knowledge 和中国期刊全文数据库。采用荟萃分析比较不同治疗方法的效果。
纳入 7 项研究，共 1208 例患者。两组患者在暂时性喉返神经（RLN）麻痹、永久性 RLN 麻痹、暂时性低钙血症、永久性低钙血症、血肿和伤口感染方面的差异均无统计学意义。
对于部分术前诊断不明确或甲状腺全切除术后复发的 DTC 患者，选择性施行甲状腺全切除术是可行的，且具有可接受的发病率。
Zotero 插件