Fischer William A, Weber David, Wohl David A
Division of Pulmonary and Critical Care Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Division of Infectious Diseases, The University of North Carolina at Chapel Hill, Chapel Hill, NC.
Clin Ther. 2015 Nov 1;37(11):2402-2410. doi: 10.1016/j.clinthera.2015.07.007. Epub 2015 Oct 9.
The recent Ebola epidemic that devastated West Africa has infected and killed more health care providers than any other outbreak in the history of this virus. An improved understanding of pathogen transmission and the institution of strategies to protect health care providers against infection are needed in infectious disease outbreaks. This review connects what is known about Ebola virus transmission with personal protective equipment (PPE) designed to arrest nosocomial transmission.
Articles pertaining to filovirus transmission and PPE in filovirus outbreaks were reviewed and findings are presented. In addition, studies that evaluated PPE and donning and doffing strategies are presented.
PPE is one step in a comprehensive infection prevention and control strategy that is required to protect health care providers. Given that the Ebola virus is primarily transmitted through direct contact of mucous membranes and cuts in the skin with infected patients and/or their bodily fluids, it is necessary to cover these potential portals of infection with PPE as part of a structured and instructed donning and doffing procedure.
Current recommendations about PPE and the donning and doffing processes are based on anecdotal experience. However, the use of non-human viruses can help provide evidence-based guidelines on both PPE and donning and doffing processes.
近期肆虐西非的埃博拉疫情感染并导致医护人员死亡的人数超过了该病毒史上的任何一次疫情爆发。在传染病爆发期间,需要更好地了解病原体传播情况,并制定保护医护人员免受感染的策略。本综述将已知的埃博拉病毒传播情况与旨在阻止医院内传播的个人防护装备(PPE)联系起来。
回顾了有关丝状病毒爆发中丝状病毒传播和个人防护装备的文章,并展示了研究结果。此外,还介绍了评估个人防护装备以及穿戴和脱卸策略的研究。
个人防护装备是保护医护人员所需的全面感染预防和控制策略的一部分。鉴于埃博拉病毒主要通过粘膜以及皮肤伤口与感染患者和/或其体液的直接接触进行传播,有必要使用个人防护装备覆盖这些潜在的感染途径,并将其作为结构化且有指导的穿戴和脱卸程序的一部分。
目前关于个人防护装备以及穿戴和脱卸过程的建议是基于轶事经验。然而,使用非人类病毒有助于为个人防护装备以及穿戴和脱卸过程提供循证指南。