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新生儿重症监护病房中的疼痛性操作与镇痛:十年间医学认知与实践有何变化?

Painful procedures and analgesia in the NICU: what has changed in the medical perception and practice in a ten-year period?

作者信息

Prestes Ana Claudia Yoshikumi, Balda Rita de Cássia Xavier, Santos Gianni Mara Silva dos, Rugolo Ligia Maria Suppo de Souza, Bentlin Maria Regina, Magalhães Mauricio, Pachi Paulo Roberto, Marba Sergio Tadeu Martins, Caldas Jamil Pedro de Siqueira, Guinsburg Ruth

机构信息

Division of Neonatal Medicine, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.

出版信息

J Pediatr (Rio J). 2016 Jan-Feb;92(1):88-95. doi: 10.1016/j.jped.2015.04.009. Epub 2015 Oct 9.

Abstract

OBJECTIVE

To compare the use of analgesia versus neonatologists' perception regarding analgesic use in painful procedures in the years 2001, 2006, and 2011.

METHODS

This was a prospective cohort study of all newborns admitted to four university neonatal intensive care units during one month in 2001, 2006, and 2011. The frequency of analgesic prescription for painful procedures was evaluated. Of the 202 neonatologists, 188 answered a questionnaire giving their opinion on the intensity of pain during lumbar puncture, tracheal intubation, mechanical ventilation, and postoperative period using a 10-cm visual analogic scale (VAS; pain >3cm).

RESULTS

For lumbar puncture, 12% (2001), 43% (2006), and 36% (2011) were performed using analgesia. Among the neonatologists, 40-50% reported VAS >3 for lumbar puncture in all study periods. For intubation, 30% received analgesia in the study periods, and 35% (2001), 55% (2006), and 73% (2011) of the neonatologists reported VAS >3 and would prescribe analgesia for this procedure. As for mechanical ventilation, 45% (2001), 64% (2006), and 48% (2011) of patient-days were under analgesia; 56% (2001), 57% (2006), and 26% (2011) of neonatologists reported VAS >3 and said they would use analgesia during mechanical ventilation. For the first three post-operative days, 37% (2001), 78% (2006), and 89% (2011) of the patients received analgesia and more than 90% of neonatologists reported VAS >3 for major surgeries.

CONCLUSIONS

Despite an increase in the medical perception of neonatal pain and in analgesic use during painful procedures, the gap between clinical practice and neonatologist perception of analgesia need did not change during the ten-year period.

摘要

目的

比较2001年、2006年和2011年疼痛性操作中镇痛的使用情况与新生儿科医生对镇痛使用的认知。

方法

这是一项对2001年、2006年和2011年期间在四家大学新生儿重症监护病房住院一个月的所有新生儿进行的前瞻性队列研究。评估了疼痛性操作的镇痛处方频率。在202名新生儿科医生中,188人回答了一份问卷,使用10厘米视觉模拟量表(VAS;疼痛>3厘米)对他们对腰椎穿刺、气管插管、机械通气和术后疼痛强度的看法进行了调查。

结果

对于腰椎穿刺,使用镇痛的比例分别为12%(2001年)、43%(2006年)和36%(2011年)。在所有研究期间,40%-50%的新生儿科医生报告腰椎穿刺的VAS>3。对于气管插管,在研究期间30%的患者接受了镇痛,35%(2001年)、55%(2006年)和73%(2011年)的新生儿科医生报告VAS>3,并表示会为此操作开具镇痛药物。至于机械通气,45%(2001年)、64%(2006年)和48%(2011年)的患者日接受了镇痛;56%(2001年)、57%(2006年)和26%(2011年)的新生儿科医生报告VAS>3,并表示会在机械通气期间使用镇痛。在术后的前三天,37%(2001年)、78%(2006年)和89%(2011年)的患者接受了镇痛,超过90%的新生儿科医生报告大手术后VAS>3。

结论

尽管在十年期间,医学界对新生儿疼痛的认知以及疼痛性操作中镇痛的使用有所增加,但临床实践与新生儿科医生对镇痛需求的认知之间的差距并未改变。

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