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食物蛋白诱导的小肠结肠炎综合征

Food Protein-Induced Enterocolitis Syndrome.

作者信息

Leonard Stephanie A, Nowak-Węgrzyn Anna

机构信息

Division of Pediatric Allergy & Immunology, Rady Children's Hospital San Diego, University of California, San Diego, 3020 Children's Way, MC 5114, San Diego, CA 92123, USA.

Division of Pediatric Allergy, Department of Pediatrics, Jaffe Food Allergy Institute, Icahn School of Medicine at Mount Sinai, Box 1198, One Gustave L. Levy Place, New York, NY 10029, USA.

出版信息

Pediatr Clin North Am. 2015 Dec;62(6):1463-77. doi: 10.1016/j.pcl.2015.07.011.

Abstract

Food protein-induced enterocolitis syndrome (FPIES) is a rare, non-immunoglobulin E-mediated gastrointestinal food allergy primarily diagnosed in infancy, but has also been reported in older children and adults. Acute FPIES reactions typically present with delayed, repetitive vomiting, lethargy, and pallor within 1 to 4 hours of food ingestion. Chronic FPIES typically presents with protracted vomiting and/or diarrhea, and weight loss or poor growth. Common foods triggering FPIES include cow's milk, soy, rice, oats, fish, and egg. More detailed diagnostic criteria may help in increasing awareness of FPIES and reducing delayed diagnoses or misdiagnoses.

摘要

食物蛋白诱导的小肠结肠炎综合征(FPIES)是一种罕见的、非免疫球蛋白E介导的胃肠道食物过敏,主要在婴儿期被诊断出来,但也有报道称在大龄儿童和成人中出现。急性FPIES反应通常在摄入食物后1至4小时内出现延迟性、反复呕吐、嗜睡和面色苍白。慢性FPIES通常表现为持续性呕吐和/或腹泻,以及体重减轻或生长发育不良。引发FPIES的常见食物包括牛奶、大豆、大米、燕麦、鱼和鸡蛋。更详细的诊断标准可能有助于提高对FPIES的认识,并减少延迟诊断或误诊。

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