State Key Laboratory of Fluid Power and Mechatronic Systems, Zhejiang University, Hangzhou, 310027, China.
School of Mechanical Engineering, Zhejiang University, Hangzhou, 310027, China.
Nat Commun. 2024 May 30;15(1):4597. doi: 10.1038/s41467-024-49019-0.
Wireless capsule endoscopy (WCE) offers a non-invasive evaluation of the digestive system, eliminating the need for sedation and the risks associated with conventional endoscopic procedures. Its significance lies in diagnosing gastrointestinal tissue irregularities, especially in the small intestine. However, existing commercial WCE devices face limitations, such as the absence of autonomous lesion detection and treatment capabilities. Recent advancements in micro-electromechanical fabrication and computational methods have led to extensive research in sophisticated technology integration into commercial capsule endoscopes, intending to supersede wired endoscopes. This Review discusses the future requirements for intelligent capsule robots, providing a comparative evaluation of various methods' merits and disadvantages, and highlighting recent developments in six technologies relevant to WCE. These include near-field wireless power transmission, magnetic field active drive, ultra-wideband/intrabody communication, hybrid localization, AI-based autonomous lesion detection, and magnetic-controlled diagnosis and treatment. Moreover, we explore the feasibility for future "capsule surgeons".
无线胶囊内镜 (WCE) 为消化系统的非侵入性评估提供了一种手段,无需镇静且避免了传统内镜检查相关的风险。其意义在于诊断胃肠道组织异常,特别是在小肠中。然而,现有的商业 WCE 设备存在局限性,例如缺乏自主的病变检测和治疗能力。微机电制造和计算方法的最新进展促使人们广泛研究将复杂技术集成到商业胶囊内镜中,以期取代有线内镜。本综述讨论了智能胶囊机器人的未来需求,对各种方法的优缺点进行了比较评估,并重点介绍了与 WCE 相关的六项技术的最新进展。这些技术包括近场无线功率传输、磁场主动驱动、超宽带/体域通信、混合定位、基于 AI 的自主病变检测,以及磁控诊断和治疗。此外,我们还探讨了未来“胶囊外科医生”的可行性。