PTX3作为一种外源性肿瘤抑制因子发挥作用。 - Suppr

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超能文献

PTX3 acts as an extrinsic oncosuppressor.

作者信息

Bonavita Eduardo, Mantovani Alberto, Garlanda Cecilia

机构信息

Humanitas Clinical and Research Center, Rozzano (Milan), Italy.

出版信息

Oncotarget. 2015 Oct 20;6(32):32309-10. doi: 10.18632/oncotarget.4845.

DOI:10.18632/oncotarget.4845

PMID:26457877

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4741692/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f70b/4741692/9ec72f70a2b0/oncotarget-06-32309-g001.jpg

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PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer.

Cell. 2015 Feb 12;160(4):700-714. doi: 10.1016/j.cell.2015.01.004.

The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.

Immunity. 2014 Apr 17;40(4):621-32. doi: 10.1016/j.immuni.2014.02.015.

Genetic PTX3 deficiency and aspergillosis in stem-cell transplantation.

N Engl J Med. 2014 Jan 30;370(5):421-32. doi: 10.1056/NEJMoa1211161.

An integrated view of humoral innate immunity: pentraxins as a paradigm.

Annu Rev Immunol. 2010;28:157-83. doi: 10.1146/annurev-immunol-030409-101305.

Modulation of the antitumor immune response by complement.

Nat Immunol. 2008 Nov;9(11):1225-35. doi: 10.1038/ni.1655. Epub 2008 Sep 28.

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Early neoplastic progression is complement independent.

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相似文献

PTX3 acts as an extrinsic oncosuppressor.

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Tissue Antigens. 2011 Apr;77(4):271-82. doi: 10.1111/j.1399-0039.2011.01645.x.

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Trends Mol Med. 2016 Jun;22(6):497-510. doi: 10.1016/j.molmed.2016.04.007. Epub 2016 May 11.

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引用本文的文献

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Brain Commun. 2022 Sep 19;4(5):fcac235. doi: 10.1093/braincomms/fcac235. eCollection 2022.

Role of Complement in Regulating Inflammation Processes in Renal and Prostate Cancers.

Cells. 2021 Sep 15;10(9):2426. doi: 10.3390/cells10092426.

Serum pentraxin 3 as a biomarker of hepatocellular carcinoma in chronic hepatitis B virus infection.

Sci Rep. 2020 Nov 20;10(1):20276. doi: 10.1038/s41598-020-77332-3.

Jie Du Tong Ye San Prevents N-Nitrosomethylbenzylamine-Induced Esophageal Carcinogenesis via Inhibition of Inflammation and Proliferation.

Evid Based Complement Alternat Med. 2019 May 20;2019:5752670. doi: 10.1155/2019/5752670. eCollection 2019.

Knockdown of Pentraxin 3 suppresses tumorigenicity and metastasis of human cervical cancer cells.

Sci Rep. 2016 Jul 5;6:29385. doi: 10.1038/srep29385.

本文引用的文献

Complement activation promotes colitis-associated carcinogenesis through activating intestinal IL-1β/IL-17A axis.

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