Shenoy Vijendra S, Kamath M Panduranga, Sreedharan Suja, Suhas S S
Department of ENT and Head and Neck Surgery, Kasturba Medical College, Manipal University, Mangalore, Karnataka, India.
J Cancer Res Ther. 2015 Jul-Sep;11(3):652. doi: 10.4103/0973-1482.138001.
Adenoid cystic carcinomas (ACC) of the head and neck are relatively rare tumors, consisting of approximately 10-15% of all salivary gland neoplasms. ACC, a slow-growing aggressive malignant tumor of salivary gland commonly seen in the submandibular, sublingual, minor salivary glands is seldom found in the parotid. Calculus, the common cause of salivary gland dysfunction is usually identified in submandibular salivary gland because of its duct anatomy and physiochemical characteristic serous secretion. We report an unusual case of co-existent presentation of ACC with salivary calculi in the parotid gland which is never been reported in the literature. Co-existence of ductal calculi and ACC is rare. Presence of parotid calculus could be due to long standing ductal obstruction by the slow-growing ACC of the parotid or other possibility is that the malignancy could have developed because of chronic irritation by parotid calculi. Confirmatory studies are required to understand its mutual pathological association.
头颈部腺样囊性癌(ACC)是相对罕见的肿瘤,约占所有涎腺肿瘤的10% - 15%。ACC是涎腺一种生长缓慢但侵袭性强的恶性肿瘤,常见于下颌下腺、舌下腺和小涎腺,很少见于腮腺。结石是涎腺功能障碍的常见原因,由于下颌下腺的导管解剖结构和浆液性分泌的理化特性,结石通常在该腺体中被发现。我们报告了一例腮腺中腺样囊性癌与涎腺结石并存的罕见病例,这在文献中从未有过报道。导管结石与ACC并存的情况很少见。腮腺结石的存在可能是由于腮腺生长缓慢的ACC长期阻塞导管,或者另一种可能性是恶性肿瘤可能是由腮腺结石的慢性刺激发展而来。需要进行进一步的研究来了解它们之间的相互病理关系。