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涎腺癌中的钙化酷似涎石病——影像学诊断陷阱:两例报告及文献简要回顾

Calcification in Salivary Gland Cancer Mimicking Sialolithiasis-A Diagnostic Pitfall on Imaging: Report of Two Cases and Brief Review of the Literature.

作者信息

Thimsen Vivian, Fauck Vanessa, Wiesmüller Marco, Agaimy Abbas, Schapher Mirco, Iro Heinrich, Koch Michael, Mantsopoulos Konstantinos

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.

Department of Radiology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.

出版信息

J Clin Med. 2022 Jun 10;11(12):3329. doi: 10.3390/jcm11123329.

DOI:10.3390/jcm11123329
PMID:35743400
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9224696/
Abstract

Sialolithiasis is the most common cause of calcifications detected with ultrasound in patients with chronic inflammatory symptoms and swellings of the salivary glands. Other differential diagnoses of calcifications are extremely rare and mostly benign. Case report and literature review. Two rare cases of malignant parotid gland tumors with calcifications in a localization typical for sialolithiasis, which were mistaken for salivary calculi based on image findings, are presented. This report intends to highlight the pitfalls in the imaging of parotid gland diseases. Even if malignant tumors of the parotid gland with calcifications are extremely rare, in ambiguous cases, differential diagnoses should be considered carefully. A high suspicion index of the need for further diagnostics in cases with calcifications is practical and could include missing periprandial symptoms, no obstruction signs in the proximal duct, and missing evidence of sialolithiasis in sialendoscopy.

摘要

涎石病是慢性炎症症状和唾液腺肿大患者中超声检测到钙化的最常见原因。钙化的其他鉴别诊断极为罕见,且大多为良性。病例报告与文献综述。本文报告了两例罕见的腮腺恶性肿瘤病例,其钙化部位与涎石病典型部位相同,基于影像学表现被误诊为唾液腺结石。本报告旨在强调腮腺疾病影像学诊断中的陷阱。即使伴有钙化的腮腺恶性肿瘤极为罕见,但在诊断不明确的病例中,仍应仔细考虑鉴别诊断。对于有钙化的病例,提高对进一步诊断必要性的怀疑指数是可行的,这可能包括无进食相关症状、近端导管无梗阻体征以及唾液腺内镜检查无涎石病证据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/1e03099a2406/jcm-11-03329-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/4ab4e33cc140/jcm-11-03329-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/66c9f57af7a5/jcm-11-03329-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/1e03099a2406/jcm-11-03329-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/4ab4e33cc140/jcm-11-03329-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/66c9f57af7a5/jcm-11-03329-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f2c/9224696/1e03099a2406/jcm-11-03329-g003.jpg

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本文引用的文献

1
Diagnostic value of preoperative fine needle aspiration cytology in parotid gland tumors.术前细针抽吸细胞学检查在腮腺肿瘤中的诊断价值。
Diagn Cytopathol. 2020 Nov;48(11):1075-1080. doi: 10.1002/dc.24514. Epub 2020 Jun 20.
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Acinic cell carcinoma of the parotid gland: from pathogenesis to management: a literature review.腮腺的闰管细胞癌:从发病机制到治疗:文献复习。
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A Novel Sonographic Scoring Model in the Prediction of Major Salivary Gland Tumors.
一种新型超声评分模型预测主要涎腺肿瘤。
Laryngoscope. 2021 Jan;131(1):E157-E162. doi: 10.1002/lary.28591. Epub 2020 Feb 28.
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Preoperative diagnostic of parotid gland neoplasms: fine-needle aspiration cytology or core needle biopsy?腮腺肿瘤的术前诊断:细针穿刺细胞学检查还是粗针活检?
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Ultrasound Supplemented by Sialendoscopy: Diagnostic Value in Sialolithiasis.超声辅助涎腺内镜:涎石病的诊断价值。
Otolaryngol Head Neck Surg. 2018 Sep;159(3):449-455. doi: 10.1177/0194599818775946. Epub 2018 Jul 3.
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Vascular malformation with phleboliths involving the parotid gland: A case report with a review of the literature.伴有静脉石的累及腮腺的血管畸形:一例病例报告并文献复习
Ear Nose Throat J. 2015 Oct-Nov;94(10-11):E1-5.
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Adenoid cystic carcinoma of the parotid gland associated with salivary calculi: An unusual presentation.腮腺腺样囊性癌合并涎石病:一种不寻常的表现。
J Cancer Res Ther. 2015 Jul-Sep;11(3):652. doi: 10.4103/0973-1482.138001.
8
Nearly 3,000 salivary stones: some clinical and epidemiologic aspects.近3000例涎石病:一些临床和流行病学方面的情况
Laryngoscope. 2015 Aug;125(8):1879-82. doi: 10.1002/lary.25377. Epub 2015 May 21.
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Cavernous hemangioma with large phlebolith of the parotid gland.腮腺海绵状血管瘤伴巨大静脉石
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Algorithms for treatment of salivary gland obstructions.唾液腺梗阻的治疗算法。
Otolaryngol Clin North Am. 2009 Dec;42(6):1173-92, Table of Contents. doi: 10.1016/j.otc.2009.08.002.