Malhotra Kiran Preet, Husain Nuzhat
Department of Pathology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
J Cancer Res Ther. 2015 Jul-Sep;11(3):666. doi: 10.4103/0973-1482.140808.
Primary lymphomas developing in the breast constitute a rare entity. A 50-year-old female presented with a breast lump for duration of 2 months. She also had a scalp swelling since 2 days. No lymph nodal involvement was present. Histopathological examination and immunohistochemistry performed on a core needle biopsy of the breast lump revealed a diffuse large B-cell non-Hodgkin's lymphoma, an aspirate of the scalp swelling revealed progression from the primary breast lymphoma (PBL). We review the relevant literature and discuss the diagnostic aspects of extranodal lymphomas arising in the breast. Disease progression to the scalp from PBL has not been reported until date. We hereby report the first case of progression to the scalp in a case of PBL.
原发于乳腺的淋巴瘤是一种罕见的疾病。一名50岁女性因乳腺肿块就诊,肿块持续2个月。她还在2天前出现头皮肿胀。未发现淋巴结受累。对乳腺肿块进行粗针活检,组织病理学检查和免疫组化显示为弥漫性大B细胞非霍奇金淋巴瘤,头皮肿胀抽吸物显示为原发性乳腺淋巴瘤(PBL)进展而来。我们回顾相关文献并讨论乳腺外淋巴瘤的诊断方面。迄今为止,尚未有PBL进展至头皮的报道。我们在此报告首例PBL进展至头皮的病例。