Narayan Satya, Kapoor Akhil, Singhal Mukesh Kumar, Jakhar Shankar Lal, Bagri Puneet Kumar, Rajput Prakash Singh, Kumar Harvindra Singh
Department of Radiation Oncology, Acharya Tulsi Regional Cancer Treatment and Research Institute, Bikaner, Rajasthan, India.
J Cancer Res Ther. 2015 Jul-Sep;11(3):667. doi: 10.4103/0973-1482.140800.
Astroblastoma is a rare neuroepithelial primary brain tumor of uncertain origin. They form 0.45-2.8% of all the neuroglial tumors. This tumor is usually localized in the cerebral hemisphere of young adults and children. The authors report a case of low-grade astroblastoma in a 16-year-old male and review the relevant literature. The patient presented with 2 months history of progressive headache with projectile vomiting for last 2 months. He underwent gross total resection of the lesion through right temporo-occipital craniotomy. Since tumor showed no evidence of high-grade lesion, adjuvant radiotherapy was not planned. However, the patient developed recurrence of the tumor after 12 months. Localized three-dimensional conformal radiotherapy was planned. In patients harboring anaplastic astroblastoma, gross-total resection and adjuvant therapy after the initial surgery seems to be the best choice. They can be easily misdiagnosed as they are rarely encountered in clinical practice and share common radiological and histopathologic appearance with other glial neoplasms.
成星形细胞瘤是一种起源不明的罕见神经上皮性原发性脑肿瘤。它们占所有神经胶质肿瘤的0.45%-2.8%。这种肿瘤通常位于年轻成年人和儿童的大脑半球。作者报告了一例16岁男性的低级别成星形细胞瘤病例并回顾了相关文献。该患者有2个月渐进性头痛病史，近2个月伴有喷射性呕吐。他通过右颞枕开颅术对病变进行了全切。由于肿瘤未显示高级别病变的证据，因此未计划辅助放疗。然而，患者在12个月后出现肿瘤复发。于是计划进行局部三维适形放疗。对于患有间变性成星形细胞瘤的患者，初次手术后进行全切和辅助治疗似乎是最佳选择。由于它们在临床实践中很少见，并且与其他胶质肿瘤具有共同的放射学和组织病理学表现，因此很容易被误诊。
