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[抗麸质IgA水平在乳糜泻检测和监测中的意义]

[Significance of anti-gluten IgA levels for detection and monitoring of celiac disease].

作者信息

Sabbah A, Desoubry L, Heulin M G

机构信息

Laboratoire d'Immuno-Allergologie, C.H.U., Angers.

出版信息

Allerg Immunol (Paris). 1989 Jan;21(1):29-31.

PMID:2645894
Abstract

Diagnosis of coeliac disease rests in jejunal biopsy. This is recognised as a traumatic examination which today may perhaps be replaced by a biological test produced by Pharmacia in which the anti-gluten IgA is measured by the ELISA method. The sensitivity of the test reaches 100% and the specificity to 96%. This biological test makes it possible to follow the development of the coeliac illness under diet, since the anti-gluten IgA diminishes significantly, often to the normal level.

摘要

乳糜泻的诊断依赖于空肠活检。这被认为是一种有创检查,如今或许可以被法玛西亚公司生产的一种生物检测所取代,该检测通过酶联免疫吸附测定法测量抗麸质IgA。该检测的敏感性达到100%,特异性为96%。这种生物检测能够在饮食控制下跟踪乳糜泻的发展情况,因为抗麸质IgA会显著降低,常常降至正常水平。

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