Fidas A, MacDonald H L, Elton R A, McInnes A, Chisholm G D
University Department of Surgery/Urology, Western General Hospital, Edinburgh.
Br J Urol. 1989 Jan;63(1):16-20. doi: 10.1111/j.1464-410x.1989.tb05116.x.
A group of 37 patients (24 female and 13 male) with chronic urinary retention and without demonstrable mechanical obstruction had neurophysiological measurements of their lower urinary tracts to detect any neurological abnormality which might relate to the disorder. These consisted of measurements of the electrosensitivity of the dorsal nerve of the penis/clitoris and of the urethra, measurement of the sacral reflex latencies (SRL) from dorsal nerve to urethra and to anus and between urethra and anus and EMG studies of the urethral and anal sphincters. The results suggest that female patients in particular have significant neurogenic defects in the voiding reflex arcs which find their clinical expression in detrusor underactivity with urinary retention. Plain X-rays of the renal tracts (KUB films) were also studied for the presence of spina bifida occulta. The prevalence of this defect was significantly higher than in normal controls, suggesting that in some of these patients the nerve defect might be related to a tethered cord in association with spina bifida occulta.
一组37例慢性尿潴留患者（24例女性，13例男性），无明显机械性梗阻，对其下尿路进行神经生理学测量，以检测可能与该疾病相关的任何神经学异常。这些测量包括阴茎/阴蒂背神经和尿道的电敏感性测量、从背神经到尿道和肛门以及尿道与肛门之间的骶反射潜伏期（SRL）测量以及尿道和肛门括约肌的肌电图研究。结果表明，尤其是女性患者在排尿反射弧中存在明显的神经源性缺陷，这在逼尿肌活动不足伴尿潴留中表现为临床症状。还对肾盂平片（KUB片）进行了研究，以检查隐性脊柱裂的存在。该缺陷的患病率明显高于正常对照组，表明在这些患者中的一些人，神经缺陷可能与隐性脊柱裂相关的脊髓栓系有关。
