Fidas A, MacDonald H L, Elton R A, McInnes A, Brown A, Chisholm G D
University Department of Surgery/Urology, Western General Hospital, Edinburgh.
Br J Urol. 1988 Jul;62(1):46-50. doi: 10.1111/j.1464-410x.1988.tb04264.x.
Neurophysiological measurements comprising surface electromyography (EMG) of the urethral and anal sphincters, measurement of the sensory thresholds of the dorsal nerve (DN) of the clitoris and the urethra and sacral reflex latencies from the dorsal nerve to urethra and anus and from the urethra to anus were performed in 44 females with genuine stress incontinence, in order to detect any relationship between the clinical disorder and a neurogenic defect in the innervation of the muscles involved in maintaining continence. Plain X-rays of the renal tracts (KUB films) were also studied to establish whether the prevalence of spina bifida occulta was increased in this group of patients and was a likely explanation for the nerve defects. Forty-three patients were found to have abnormal neurophysiological responses and the prevalence of spina bifida occulta was 50%, which compares with a prevalence of 17% in normal female controls. Genuine stress incontinence appears to be at least partly associated with defective innervation of the lower urinary tract and it is likely that in some cases the defect may be related to the presence of spina bifida occulta.
对44名真性压力性尿失禁女性进行了神经生理学测量，包括尿道和肛门括约肌的表面肌电图（EMG）、阴蒂背神经（DN）和尿道的感觉阈值测量，以及从背神经到尿道和肛门以及从尿道到肛门的骶反射潜伏期测量，以便检测临床疾病与维持控尿相关肌肉神经支配的神经源性缺陷之间的任何关系。还研究了尿路的普通X线片（KUB片），以确定该组患者中隐性脊柱裂的患病率是否增加，以及是否可能是神经缺陷的原因。发现43例患者有异常神经生理反应，隐性脊柱裂的患病率为50%，而正常女性对照组的患病率为17%。真性压力性尿失禁似乎至少部分与下尿路神经支配缺陷有关，并且在某些情况下，缺陷可能与隐性脊柱裂的存在有关。
