Claggett M S
J Am Diet Assoc. 1989 Mar;89(3):392-6.
Alzheimer's disease is a devastating form of nonreversible dementia now affecting at least 2.5 million persons in the United States. Its course is marked by a gradual loss of memory, ability to communicate, and, eventually, physical capabilities. Appetite and food intake fluctuate with mood swings and increasing confusion. Feeding and alimentation skills regress gradually because of cognitive and physical deterioration; uncontrolled weight loss is almost inevitable in latter stages, despite quality of care. A number of etiological models exist, including some related to vitamin and mineral metabolism, although research has not yet yielded a certain cause or cure. Treatment is symptomatic relief through interdisciplinary health care intervention. Psychological, medical, nutritional, and nursing support are needed by the caregivers as well as by the patients themselves.
阿尔茨海默病是一种毁灭性的不可逆性痴呆症，目前在美国至少影响着250万人。其病程的特点是记忆力、沟通能力逐渐丧失，最终身体机能也会丧失。食欲和食物摄入量会随着情绪波动和意识混乱的加剧而波动。由于认知和身体机能的衰退，进食和营养技能会逐渐退化；尽管护理质量很高，但在后期几乎不可避免地会出现体重失控下降的情况。目前存在多种病因模型，包括一些与维生素和矿物质代谢相关的模型，不过研究尚未找到确切的病因或治愈方法。治疗方法是通过跨学科的医疗保健干预来缓解症状。护理人员以及患者本人都需要心理、医疗、营养和护理方面的支持。
