Martín Garzón Oscar Dario, Azhar Raed A, Brunacci Leonardo, Ramirez-Troche Nelson Emilio, Medina Navarro Luis, Hernández Luis Cesar, Nuñez Bragayrac Luciano, Sotelo Noguera René Javier
1 Instituto Medico La Floresta, Centro de Cirugía Robótica Mínimamente Invasiva (CIMI) , Caracas, Venezuela .
2 Department of Urology, King Abdulaziz University , Jeddah, Saudi Arabia .
J Endourol. 2016 Mar;30(3):312-8. doi: 10.1089/end.2015.0218. Epub 2015 Nov 12.
To compare preoperative, intraoperative, and postoperative variables at 1, 6, and 12 months after laparoscopic simple prostatectomy (LSP), robotic simple prostatectomy (RSP), and intrafascial robotic simple prostatectomy (IF-RSP).
From January 2003 to November 2014, 315 simple prostatectomies were performed using three techniques, LSP, RSP, and IF-RSP; of the patients who underwent these procedures, 236 met the inclusion criteria for this study.
No statistically significant difference (SSD) was found in preoperative or perioperative variables. Of the postoperative variables that were analyzed, an SSD (p > 0.01) in prostate-specific antigen levels was found, with levels of 0.07 ± 1.1 ng/mL following IF-RSP, and the detection rate of prostate adenocarcinoma (26%) and high-grade prostatic intraepithelial neoplasia (HG-PIN; 12%) was higher for IF-RSP. We also found that lower International Prostate Symptom Scores (IPSS) were associated with LSP, at 4.8 ± 3.2. Erectile function was reduced in IF-RSP patients in the first 6 months after surgery but was similar in all patient groups at 12 months after surgery; continence and other measured parameters were also similar at 12 months for all three techniques.
The IF-RSP technique is safe and effective, with results at 1-year follow-up for continence, IPSS, and Sexual Health Inventory for Men scores similar to those for the LSP and RSP techniques. IF-RSP also offers the advantages that it does not require postoperative irrigation, has an increased ability to detect prostate cancer (CA) and HG-PIN, and avoids the risk of future cancer and subsequent reintervention for possible new prostate growth.
比较腹腔镜单纯前列腺切除术(LSP)、机器人辅助单纯前列腺切除术(RSP)和筋膜内机器人辅助单纯前列腺切除术(IF-RSP)术后1个月、6个月和12个月的术前、术中和术后变量。
2003年1月至2014年11月,采用LSP、RSP和IF-RSP三种技术进行了315例单纯前列腺切除术;接受这些手术的患者中,236例符合本研究的纳入标准。
术前或围手术期变量未发现统计学显著差异(SSD)。在分析的术后变量中,前列腺特异性抗原水平存在SSD(p>0.01),IF-RSP术后该水平为0.07±1.1 ng/mL,且IF-RSP的前列腺腺癌(26%)和高级别前列腺上皮内瘤变(HG-PIN;12%)检出率更高。我们还发现,LSP患者的国际前列腺症状评分(IPSS)较低,为4.8±3.2。IF-RSP患者术后前6个月勃起功能降低,但术后12个月时所有患者组相似;三种技术在术后12个月时的控尿及其他测量参数也相似。
IF-RSP技术安全有效,1年随访时控尿、IPSS和男性性健康量表评分结果与LSP和RSP技术相似。IF-RSP还具有无需术后冲洗、检测前列腺癌(CA)和HG-PIN的能力增强以及避免未来癌症风险和后续因可能的新前列腺生长而再次干预的优点。