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经膀胱前列腺内镜腺瘤切除术,一种治疗大型良性前列腺增生的新型微创方法。我们的经验给了我们什么启示?

Endoscopic transvesical adenomectomy of the prostate, a new minimally invasive approach for large benign prostatic hyperplasia. What has our experience taught us?

作者信息

Vale Luís, Fossion Laurent

机构信息

Maxima Medical Centre, Department of Urology, Veldhoven, The Netherlands.

Centro Hospitalar Universitário São João, Department of Urology, Porto, Portugal.

出版信息

Cent European J Urol. 2020;73(4):482-489. doi: 10.5173/ceju.2020.0053.R3. Epub 2020 Oct 31.

DOI:10.5173/ceju.2020.0053.R3
PMID:33552574
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7848824/
Abstract

INTRODUCTION

Recent technical advances have made new minimally invasive techniques possible to treat large volume (>80 ml) benign prostatic hyperplasia (BPH). The endoscopic transperitoneal adenomectomy of the prostate (ETAP) is a new minimally invasive technique developed in our centre. The aim of this study was to describe the safety, efficacy and to evaluate our learning curve in ETAP.

MATERIAL AND METHODS

This was a single-centre study that enrolled eighty-eight consecutive patients with large BPH who underwent ETAP. Pre-, per- and postoperative data were prospectively collected. Statistical analysis compared the first 40 patients submitted to ETAP (Group A) with the subsequent 48 patients (Group B).

RESULTS

There were no significant differences in the surgical procedure between groups. The median operating time was 94 (80-110) minutes and the estimated blood loss 150 (100-300) ml. There were no perioperative blood transfusions nor any conversions to open approach needed. Median hospital stay was 3 (3-5) days and catheter was removed mainly at day 9 (5-11). The median Qmax improved from 8.0 (6.2-9.9) ml/s to 15.0 (11.5-23.0) ml/s postoperatively and the median International Prostate Symptom Score (IPSS) score decreased from 20 (15-24) to 6 (4-11) after the procedure.

CONCLUSIONS

ETAP is a secure and feasible minimally invasive technique for treatment of large BPH. The functional outcomes of this technique are consistent and promising.

摘要

引言

最近的技术进步使治疗大体积(>80毫升)良性前列腺增生(BPH)的新微创技术成为可能。经腹前列腺内镜腺瘤切除术(ETAP)是我们中心开发的一种新的微创技术。本研究的目的是描述ETAP的安全性、有效性并评估我们的学习曲线。

材料与方法

这是一项单中心研究,纳入了88例连续接受ETAP的大体积BPH患者。前瞻性收集术前、术中及术后数据。统计分析比较了前40例接受ETAP的患者(A组)与随后的48例患者(B组)。

结果

两组手术过程无显著差异。中位手术时间为94(80 - 110)分钟,估计失血量为150(100 - 300)毫升。围手术期无输血情况,也无需转为开放手术。中位住院时间为3(3 - 5)天,导尿管主要在第9天(5 - 11天)拔除。术后最大尿流率(Qmax)中位数从8.0(6.2 - 9.9)毫升/秒提高到15.0(11.5 - 23.0)毫升/秒,国际前列腺症状评分(IPSS)中位数从20(15 - 24)降至6(4 - 11)。

结论

ETAP是一种安全可行的治疗大体积BPH的微创技术。该技术的功能结果一致且前景良好。

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Endoscopic Transvesical Adenomectomy of the Prostate, a New Minimal Invasive Approach for Large Benign Prostate Hyperplasia. A Description of the Technique and the Results of the First 40 Patients.
Urology. 2019 Mar;125:174-178. doi: 10.1016/j.urology.2018.12.031. Epub 2019 Jan 4.
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