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机器人辅助单纯前列腺切除术治疗前列腺重量大于 100 克。

Robot-assisted simple prostatectomy for prostates greater than 100 g.

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai, The Mount Sinai Hospital, 1425 Madison Avenue, New York, NY, 10029, USA.

Department of Urology, Alexandria, Egypt.

出版信息

World J Urol. 2023 Apr;41(4):1169-1174. doi: 10.1007/s00345-023-04326-x. Epub 2023 Mar 16.

Abstract

PURPOSE

Efforts are ongoing to treat severe benign prostatic hyperplasia as traditional endoscopic treatment options are often difficult to perform and associated with significant complications. This manuscript highlights our initial experience of robot-assisted simple prostatectomy [RASP] with minimum a year follow-up. We also compared our outcomes with published literature.

METHODS

After an Institution Review Board approval, we gathered data of 50 cases of RASP between Jan 2014 and May 2021. Patients with prostate volume > 100 cc [calculated from magnetic resonance imaging (MRI)] and prostate biopsy confirmed benign prostate were candidates for RASP. Patients underwent RASP via transperitoneal route either by suprapubic or trans-vesical approach. Preoperative demographics, peri-operative parameters and post-operative parameters such as hospital stay, catheter removal, urinary continence and uroflow were recorded in standard database and presented as descriptive statistics.

RESULTS

Patients presented with a baseline median International Prostate Symptom Score (IPSS) of 23 (inter-quartile range (IQR) 21,25) and a median PSA of 7.7 ng/ml (IQR 6.4,8.7). Median preoperative prostate volume was 167 ml (IQR, 136,198 ml). Median console time was 118 min, and median estimated blood loss was 148 ml (IQR 130, 167 ml). None of our cohort needed intraoperative transfusion, conversion to open surgery or developed any complications. Median time to Foley removal was 10 days (IQR 8,12). Significant drop in the IPSS score and improvement in Qmax was noted over the period of follow-up.

CONCLUSION

RASP is associated with considerable improvements in urinary symptoms. However, comparative studies with endoscopic treatment options of large prostatic adenomas are warranted and ideally include cost analysis of different procedures.

摘要

目的

目前正在努力治疗严重的良性前列腺增生,因为传统的内镜治疗方法往往难以实施,并伴有严重的并发症。本文重点介绍了我们在机器人辅助单纯前列腺切除术(RASP)方面的初步经验,随访时间至少为 1 年。我们还将我们的结果与已发表的文献进行了比较。

方法

在机构审查委员会批准后,我们收集了 2014 年 1 月至 2021 年 5 月期间 50 例 RASP 病例的数据。前列腺体积>100 cc[根据磁共振成像(MRI)计算]和前列腺活检证实为良性前列腺的患者为 RASP 候选者。患者通过经腹腔途径接受 RASP 手术,采用耻骨上或经膀胱入路。在标准数据库中记录术前人口统计学、围手术期参数和术后参数,如住院时间、导管去除、尿控和尿流率,并以描述性统计数据呈现。

结果

患者的基线国际前列腺症状评分(IPSS)中位数为 23(四分位距(IQR)21,25),前列腺特异性抗原(PSA)中位数为 7.7ng/ml(IQR 6.4,8.7)。术前前列腺体积中位数为 167ml(IQR,136,198ml)。控制台时间中位数为 118 分钟,估计失血量中位数为 148ml(IQR 130,167ml)。我们的队列中没有患者需要术中输血、转为开放性手术或发生任何并发症。导尿管拔除时间中位数为 10 天(IQR 8,12)。在随访期间,IPSS 评分显著下降,Qmax 得到改善。

结论

RASP 可显著改善尿症状。然而,需要与大前列腺腺瘤的内镜治疗方法进行比较研究,理想情况下还包括对不同手术程序的成本分析。

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