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孕期及哺乳期患者的影像学检查

Imaging Pregnant and Lactating Patients.

作者信息

Tirada Nikki, Dreizin David, Khati Nadia J, Akin Esma A, Zeman Robert K

机构信息

From the Department of Radiology, George Washington University Hospital, 900 23rd St NW, Washington, DC 20037 (N.T., N.J.K., E.A.A., R.K.Z.); and Department of Diagnostic Radiology, University of Maryland Medical Center and R Adams Cowley Shock Trauma Center, Baltimore, Md (D.D).

出版信息

Radiographics. 2015 Oct;35(6):1751-65. doi: 10.1148/rg.2015150031.

Abstract

As use of imaging in the evaluation of pregnant and lactating patients continues to increase, misperceptions of radiation and safety risks have proliferated, which has led to often unwarranted concerns among patients and clinicians. When radiologic examinations are appropriately used, the benefits derived from the information gained usually outweigh the risks. This review describes appropriateness and safety issues, estimated doses for imaging examinations that use iodizing radiation (ie, radiography, computed tomography, nuclear scintigraphy, and fluoroscopically guided interventional radiology), radiation risks to the mother and conceptus during various stages of pregnancy, and use of iodinated or gadolinium-based contrast agents and radiotracers in pregnant and lactating women. Maternal radiation risk must be weighed with the potential consequences of missing a life-threatening diagnosis such as pulmonary embolus. Fetal risks (ie, spontaneous abortion, teratogenesis, or carcinogenesis) vary with gestational age and imaging modality and should be considered in the context of the potential benefit of medically necessary diagnostic imaging. When feasible and medically indicated, modalities that do not use ionizing radiation (eg, magnetic resonance imaging) are preferred in pregnant and lactating patients. Radiologists should strive to minimize risks of radiation to the mother and fetus, counsel patients effectively, and promote a realistic understanding of risks related to imaging during pregnancy and lactation.

摘要

随着影像学在评估妊娠和哺乳期患者中的应用持续增加,对辐射和安全风险的误解也不断扩散,这导致患者和临床医生常常产生无端的担忧。当合理使用放射学检查时,所获得信息带来的益处通常超过风险。本综述描述了适宜性和安全性问题、使用电离辐射的影像学检查(即X线摄影、计算机断层扫描、核闪烁成像和荧光透视引导介入放射学)的估计剂量、孕期各阶段母亲和胎儿所面临的辐射风险,以及碘化或钆基造影剂和放射性示踪剂在孕妇和哺乳期妇女中的使用。必须权衡母亲的辐射风险与漏诊危及生命的诊断(如肺栓塞)的潜在后果。胎儿风险(即自然流产、致畸或致癌)因孕周和成像方式而异,应在医学必要的诊断性影像学潜在益处的背景下予以考虑。在可行且有医学指征时,孕妇和哺乳期患者首选不使用电离辐射的检查方式(如磁共振成像)。放射科医生应努力将对母亲和胎儿的辐射风险降至最低,有效地为患者提供咨询,并促进对妊娠和哺乳期影像学相关风险的现实理解。

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