Koppen Ilan J N, Di Lorenzo Carlo, Saps Miguel, Dinning Phil G, Yacob Desale, Levitt Marc A, Benninga Marc A
a Department of Pediatric Gastroenterology and Nutrition , Emma Children's Hospital/Academic Medical Center , Amsterdam , The Netherlands.
b Division of Pediatric Gastroenterology, Hepatology, and Nutrition , Nationwide Children's Hospital , Columbus , OH , USA.
Expert Rev Gastroenterol Hepatol. 2016;10(1):141-55. doi: 10.1586/17474124.2016.1098533. Epub 2015 Oct 14.
Recent developments in the evaluation and treatment of childhood constipation are likely to influence the way we deal with pediatric defecation disorders in the near future. Innovations in both colonic and anorectal manometry are leading to novel insights into functional defecation disorders in children. Promising results have been achieved with innovative therapies such as electrical stimulation and new drugs with targets that differ from conventional pharmacological treatments. Also, new surgical approaches, guided by manometric findings, have led to improvement in patient outcome. Finally, utilization of non-pharmacological interventions such as fiber and probiotics has been a field of particular interest in recent years. The aim of this article is to provide an update on these and other novel diagnostic and therapeutic tools related to childhood constipation.
儿童便秘评估与治疗方面的最新进展，很可能在不久的将来影响我们处理小儿排便障碍的方式。结肠和肛门直肠测压技术的创新，正带来对儿童功能性排便障碍的全新认识。诸如电刺激等创新疗法以及与传统药物治疗靶点不同的新药，已取得了令人鼓舞的成果。此外，在测压结果指导下的新手术方法，也使患者预后得到改善。最后，近年来，纤维和益生菌等非药物干预措施的应用一直是特别受关注的领域。本文旨在就这些以及其他与儿童便秘相关的新型诊断和治疗工具提供最新信息。
