Tzelikis Patrick Frensel, Fenelon Eduardo Muniz, Yoshimoto Rodrigo Rodrigues, Rascop Gustavo Peixoto, Queiroz Rodrigo Lafetá, Hida Wilson Takashi
Cornea and External Diseases Department, Hospital Oftalmológico de Brasília, Brasilia, DF, BR.
Arq Bras Oftalmol. 2015 Sep-Oct;78(5):310-2. doi: 10.5935/0004-2749.20150081.
To assess patient characteristics, risk factors, outcomes, and the treatment of wound dehiscence (WD) in patients after corneal keratoplasty.
Retrospective chart review of 11 eyes of 11 patients with corneal grafts who underwent repair of WD from January 1, 2004 to December 31, 2012 at Hospital Oftalmologico de Brasilia.
Eight (72.7%) patients were men and three were women. Six (54.5%) patients had deep anterior lamellar keratoplasty (DALK) and 5 had penetrating keratoplasty. The mean age at trauma was 31.1 years. The mean time from corneal keratoplasty to WD was 12.82 months (range, 3-33 months). The mean best-corrected visual acuity of patients before trauma was 20/60 (0.48 logMAR) and after final treatment was 20/160 (0.90 logMAR) (P=0.15). In one case, visual acuity decreased to no light perception because of retinal detachment and phthisis bulbi. Accidental blunt trauma and fall were the most common causes of WD.
Patients who undergo corneal keratoplasty have a life-long risk of WD. The full-thickness rupture at the graft-host junction in our study suggests that the junction remains vulnerable, even following DALK, and can rupture with trauma. In our series, depending upon the severity of the trauma, postkeratoplastic WD can be associated with a good visual prognosis.
评估角膜移植术后患者伤口裂开(WD)的患者特征、危险因素、结局及治疗情况。
对2004年1月1日至2012年12月31日在巴西利亚眼科医院接受WD修复的11例角膜移植患者的11只眼进行回顾性病历审查。
8例(72.7%)患者为男性,3例为女性。6例(54.5%)患者接受了深板层角膜移植术(DALK),5例接受了穿透性角膜移植术。受伤时的平均年龄为31.1岁。从角膜移植到WD的平均时间为12.82个月(范围3 - 33个月)。患者受伤前的平均最佳矫正视力为20/60(0.48 logMAR),最终治疗后的平均最佳矫正视力为20/160(0.90 logMAR)(P = 0.15)。1例患者因视网膜脱离和眼球痨导致视力下降至无光感。意外钝挫伤和跌倒为WD最常见的原因。
接受角膜移植的患者终生存在WD风险。我们研究中移植片与宿主交界处的全层破裂表明,即使在DALK术后,该交界处仍易受损,可因外伤而破裂。在我们的系列研究中,根据外伤的严重程度,角膜移植术后WD可能具有良好的视力预后。