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深层板层角膜移植术后创伤性伤口裂开。

Traumatic wound dehiscence after deep anterior lamellar keratoplasty.

机构信息

Ophthalmology Department, Medical Faculty, Balıkesir University, Balıkesir, Turkey.

出版信息

Am J Ophthalmol. 2013 Oct;156(4):767-72. doi: 10.1016/j.ajo.2013.05.014. Epub 2013 Jul 4.

DOI:10.1016/j.ajo.2013.05.014
PMID:23831222
Abstract

PURPOSE

To analyze the outcomes of traumatic wound dehiscence after deep anterior lamellar keratoplasty (DALK).

DESIGN

Retrospective and interventional case series.

SETTING

Single hospital.

PATIENTS

A total of 338 consecutive cases were reviewed. Eleven eyes that had wound dehiscence related to ocular trauma were included.

MAIN OUTCOME MEASURES

Incidence and causes, best-corrected visual acuity (BCVA), and endothelial cell density were evaluated. Complications and secondary surgeries were recorded.

RESULTS

Seven patients were male (63.6%) and 4 patients were female (36.4%), with a mean age of 30.6 years (range, 24-40 years). The incidence of wound dehiscence was 3.2% (11/338). The mean interval between the initial DALK procedure and wound dehiscence was 9.45 months (range, 2-16 months). The mean follow-up time was 6 years. The most common trauma was a fist blow injury (36.3%). Descemet membrane perforation was observed in 8 eyes (72.7%); lens damage and vitreous prolapse occurred in 2 eyes (18.1%). The final BCVA was 0.51 and was maintained in 4 eyes (36.3%). At the final visit, 10 grafts (90.9%) were clear. The mean endothelial cell loss was 55.8% between before DALK and last visit.

CONCLUSION

Although the intact Descemet membrane protects against dehiscing traumas after DALK, a relative weakness at the graft-host junction tends to persist and a severe deforming force may result in graft dehiscence. This case series indicates that despite the fact that the visual results following the repair are acceptable, corneal endothelium seems to be subjected to severe damage, which puts graft survival chances at risk in the long term.

摘要

目的

分析深板层角膜移植术后创伤性伤口裂开的结果。

设计

回顾性和干预性病例系列。

地点

单家医院。

患者

共回顾了 338 例连续病例。纳入了 11 例与眼外伤相关的伤口裂开的眼。

主要观察指标

发生率和原因、最佳矫正视力(BCVA)和内皮细胞密度。记录并发症和二次手术。

结果

7 例患者为男性(63.6%),4 例患者为女性(36.4%),平均年龄 30.6 岁(范围,24-40 岁)。伤口裂开的发生率为 3.2%(11/338)。初次 DALK 手术后至伤口裂开的平均间隔时间为 9.45 个月(范围,2-16 个月)。平均随访时间为 6 年。最常见的创伤是拳头打击伤(36.3%)。8 只眼(72.7%)观察到后弹力膜穿孔;2 只眼(18.1%)发生晶状体损伤和玻璃体脱出。最终 BCVA 为 0.51,4 只眼(36.3%)保持不变。末次随访时,10 个移植物(90.9%)透明。DALK 前后内皮细胞丢失平均值为 55.8%。

结论

尽管完整的后弹力膜在 DALK 后可防止外伤性裂开,但移植物-宿主交界处的相对薄弱仍持续存在,严重的变形力可能导致移植物裂开。本病例系列表明,尽管修复后的视力结果可以接受,但角膜内皮似乎受到严重损伤,这在长期内使移植物的存活率面临风险。

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