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局部应用新鲜冷冻血浆成功治疗婴儿木样结膜炎。

Successful treatment of ligneous conjunctivitis with topical fresh frozen plasma in an infant.

作者信息

Tunay Zuhal Özen, Özdemir Özdemir, Acar Damla, Gül Ece, Akbay Serap

机构信息

Ophthalmology Department, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, TR.

Biochemistry Department, Zekai Tahir Burak Women's Health Education and Research Hospital, Ankara, TR.

出版信息

Arq Bras Oftalmol. 2015 Sep-Oct;78(5):318-9. doi: 10.5935/0004-2749.20150083.

DOI:10.5935/0004-2749.20150083
PMID:26466233
Abstract

A 6-month-old female infant presented to our clinic with bilateral eyelid swelling, yellowish-white membranes under both lids, and mucoid ocular discharge. Her aunt had similar ocular problems that were undiagnosed. The conjunctival membranes were excised and histopathological investigation of these membranes showed ligneous conjunctivitis. Further, laboratory examination revealed plasminogen deficiency. A good response was observed to topical fresh frozen plasma (FFP) treatment without systemic therapy, and the membranes did not recur during the treatment. Topical FFP treatment may facilitate rapid rehabilitation and prevent recurrence in patients with ligneous conjunctivitis.

摘要

一名6个月大的女婴因双侧眼睑肿胀、双侧眼睑下有黄白色膜状物及黏液性眼部分泌物前来我院就诊。她的姑姑有类似的眼部问题,但未得到诊断。切除结膜组织,对这些组织进行组织病理学检查显示为木质化性结膜炎。此外,实验室检查发现纤溶酶原缺乏。在未进行全身治疗的情况下,局部应用新鲜冰冻血浆(FFP)治疗取得了良好效果,治疗期间膜状物未复发。局部应用FFP治疗可能有助于木质化性结膜炎患者快速康复并预防复发。

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引用本文的文献

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Ligneous conjunctivitis: Fresh-frozen plasma and heparin use intra-and postoperatively, a report of two cases.细菌性结膜炎:术中及术后使用新鲜冷冻血浆和肝素,两例报告。
Arq Bras Oftalmol. 2024 Mar 22;87(3):e20220288. doi: 10.5935/0004-2749.2022-0288. eCollection 2024.
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Combined medical and surgical approach in the management of ligneous conjunctivitis in a pediatric patient: A case report.小儿木样结膜炎治疗中的联合药物与手术方法:一例报告
Int J Surg Case Rep. 2023 Sep;110:108568. doi: 10.1016/j.ijscr.2023.108568. Epub 2023 Jul 27.