Watts Patrick, Agha Shahab H, Mameesh Maha, Conor Phillip, Ganesh Anuradha, Al-Mujaini Abdullah, Jewsbury Hugh, Pathare Anil, Al-Rawas Abdulhakim
Departments of Ophthalmology, University Hospital Wales, Cardiff, United Kingdom.
Department of Ophthalmology, Sultan Qaboos University Hospital, Muscat, Oman.
J AAPOS. 2019 Feb;23(1):42-45.e1. doi: 10.1016/j.jaapos.2018.05.011. Epub 2018 Aug 27.
Ligneous conjunctivitis is a rare form of chronic recurrent membranous conjunctivitis with reduced plasminogen activity. It is characterized by the formation of characteristic firm ("woody") membranes on the tarsal conjunctiva. Similar lesions may occur on other mucous membranes. When treated with local excision, ligneous conjunctivitis is invariably associated with recurrences. Various therapeutic modalities, including topical heparin, cyclosporine, fresh frozen plasma (FFP), plasminogen, and amniotic membrane transplantation have been reported to reduce postoperative recurrences. We present 2 cases of recurrent ligneous conjunctivitis in children successfully managed with surgical excision under cover of FFP transfusion, amniotic membrane grafting, and combined with concomitant postoperative administration of topical heparin, steroids.
木质化性结膜炎是一种罕见的慢性复发性膜性结膜炎，伴有纤溶酶原活性降低。其特征是在睑结膜上形成特征性的坚实（“木质样”）膜。其他粘膜也可能出现类似病变。采用局部切除治疗时，木质化性结膜炎总是会复发。据报道，包括局部应用肝素、环孢素、新鲜冰冻血浆（FFP）、纤溶酶原和羊膜移植在内的各种治疗方法可减少术后复发。我们报告2例儿童复发性木质化性结膜炎，在FFP输血、羊膜移植的掩护下成功进行手术切除，并联合术后局部应用肝素、类固醇治疗。
