Lopez N, Grabowski J P, De Santiago J, Zapardiel I
a Department of Gynaecological Oncology , La Paz University Hospital , Madrid , Spain.
b Department of Gynecology , European Competence Center for Ovarian Cancer, Charité-University Medicine of Berlin , Berlin , Germany.
J Obstet Gynaecol. 2016 May;36(4):450-4. doi: 10.3109/01443615.2015.1065234. Epub 2015 Oct 14.
Carcinoma of the recto-vaginal septum is an extremely rare entity. We performed a MEDLINE-based search on recto-vaginal septum carcinoma, focussing on its management, in order to clarify which are the best treatment options for this disease. In addition an unpublished case report has been added to the review. 34 case reports were included in our review. Surgery and adjuvant chemoradiation therapy seem to be the most common treatment option. However, since primary surgical treatment leads to mutilation by removing a large portion of the vagina and the anal sphincter with a permanent terminal colostomy, primary platinum-based chemoradiation therapy could be considered. In case of extragastrointestinal stromal tumours primary surgical treatment seems to be the best option. Due to the rarity of this entity only limited data is available. Therefore further investigation is necessary.
直肠阴道隔癌是一种极其罕见的疾病。我们基于医学文献数据库（MEDLINE）对直肠阴道隔癌进行了检索，重点关注其治疗方法，以明确针对该疾病的最佳治疗方案。此外，一篇未发表的病例报告也被纳入了本综述。我们的综述纳入了34篇病例报告。手术及辅助放化疗似乎是最常见的治疗选择。然而，由于初次手术治疗会通过切除大部分阴道和肛门括约肌并进行永久性末端结肠造口术而导致毁伤，因此可以考虑以铂类为基础的初次放化疗。对于胃肠道外间质瘤，初次手术治疗似乎是最佳选择。由于该疾病罕见，可用数据有限。因此，有必要进行进一步研究。
