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一名BRCA1基因阳性患者在进行降低风险手术后数年出现直肠阴道隔肿物：病例报告

A rectovaginal septum mass in a BRCA1 positive patient years after risk reducing surgery: A case report.

作者信息

Blankenship Logan, Lyons Yasmin A, Dao Campi Haisar, Valente Philip T, Barnes Laura, Kost Edward R

机构信息

University of Texas at San Antonio Health Science Center Long School of Medicine, 7703 Floyd Curl Drive, San Antonio, TX 78229, United States.

出版信息

Gynecol Oncol Rep. 2021 May 5;36:100772. doi: 10.1016/j.gore.2021.100772. eCollection 2021 May.

DOI:10.1016/j.gore.2021.100772
PMID:34026998
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8129930/
Abstract

•Rectovaginal septum mass in BRCA1 positive patient after risk reducing BSO years prior.•Papillary serous carcinoma presenting as a rectovaginal septum mass.•PAOLA-1 trial discussion for rectovaginal septum mass in BRCA1 positive patient.

摘要

• 一名BRCA1基因阳性患者在数年前进行降低风险的双侧输卵管卵巢切除术后出现直肠阴道隔肿物。

• 以直肠阴道隔肿物形式表现的乳头状浆液性癌。

• 关于BRCA1基因阳性患者直肠阴道隔肿物的PAOLA-1试验讨论。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/cf0492a48e82/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/1ad659c95e30/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/39fa9cb9fe8e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/cf0492a48e82/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/1ad659c95e30/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/39fa9cb9fe8e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/465c/8129930/cf0492a48e82/gr3.jpg

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A rectovaginal septum mass in a BRCA1 positive patient years after risk reducing surgery: A case report.一名BRCA1基因阳性患者在进行降低风险手术后数年出现直肠阴道隔肿物：病例报告
Gynecol Oncol Rep. 2021 May 5;36:100772. doi: 10.1016/j.gore.2021.100772. eCollection 2021 May.
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本文引用的文献

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Olaparib plus Bevacizumab as First-Line Maintenance in Ovarian Cancer.奥拉帕利联合贝伐珠单抗作为卵巢癌一线维持治疗。
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Risk-Reducing Surgery in Hereditary Breast and Ovarian Cancer.遗传性乳腺癌和卵巢癌的降风险手术
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Carcinoma of the recto-vaginal septum. Comprehensive literature review.直肠阴道隔癌。文献综述
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Meta-analysis of risk reduction estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriers.对BRCA1或BRCA2基因突变携带者行降低风险的输卵管卵巢切除术相关风险降低估计值的荟萃分析。
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Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2.由于BRCA1和BRCA2基因的遗传性突变导致的乳腺癌和卵巢癌风险。
Science. 2003 Oct 24;302(5645):643-6. doi: 10.1126/science.1088759.
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Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation.对携带BRCA1或BRCA2基因突变的女性进行降低风险的输卵管卵巢切除术。
N Engl J Med. 2002 May 23;346(21):1609-15. doi: 10.1056/NEJMoa020119. Epub 2002 May 20.
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Prevalence and penetrance of BRCA1 and BRCA2 mutations in a population-based series of breast cancer cases. Anglian Breast Cancer Study Group.基于人群的一系列乳腺癌病例中BRCA1和BRCA2突变的患病率及外显率。东安格利亚乳腺癌研究小组。
Br J Cancer. 2000 Nov;83(10):1301-8. doi: 10.1054/bjoc.2000.1407.
10
[Serous papillary cystadenocarcinoma of the recto-vaginal septum: a rare primary localization].直肠阴道隔浆液性乳头状囊腺癌：一种罕见的原发部位
Ann Pathol. 1999 Mar;19(1):42-5.