Bernardo Travis J, Dubrovsky Edward B
Department of Biology, Fordham University, Bronx, NY 10458, USA.
Center for Cancer, Genetic Diseases, and Gene Regulation, Fordham University, Bronx, NY 10458, USA.
Insects. 2012 Mar 22;3(1):324-38. doi: 10.3390/insects3010324.
Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH.
保幼激素（JH）负责控制许多生物学过程。在几种昆虫物种中，JH被认为是发育时间的关键调节因子，可防止幼虫生长期间变态过早开始。然而，JH作用的分子基础尚不清楚。在这篇综述中，我们重点介绍了最近的进展，这些进展证明了来自bHLH-PAS和核受体家族的转录因子在介导对JH的反应中的重要性。
