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冠状动脉搭桥手术后接受住院心脏康复治疗的患者在运动期间进行持续气道正压通气可改善步行时间:一项随机对照试验

Continuous Positive Airway Pressure During Exercise Improves Walking Time in Patients Undergoing Inpatient Cardiac Rehabilitation After Coronary Artery Bypass Graft Surgery: A RANDOMIZED CONTROLLED TRIAL.

作者信息

Pantoni Camila Bianca Falasco, Di Thommazo-Luporini Luciana, Mendes Renata Gonçalves, Caruso Flávia Cristina Rossi, Mezzalira Daniel, Arena Ross, Amaral-Neto Othon, Catai Aparecida Maria, Borghi-Silva Audrey

机构信息

Cardiopulmonary Physiotherapy Laboratory (Dr Pantoni, Dr Thommazo-Luporini, Dr Mendes, Dr Caruso, Mr Mezzalira, Dr Catai, and Dr Borghi-Silva), Nucleus of Research in Physical Exercise, Federal University of São Carlos, São Carlos, São Paulo, Brazil; Department of Physical Therapy (Dr Arena), College of Applied Health Sciences, University of Illinois at Chicago, Chicago, Illinois; and Irmandade Santa Casa Misericordia Hospital (Dr Amaral-Neto), Araraquara, São Paulo, Brazil.

出版信息

J Cardiopulm Rehabil Prev. 2016 Jan-Feb;36(1):20-7. doi: 10.1097/HCR.0000000000000144.

Abstract

PURPOSE

Continuous positive airway pressure (CPAP) has been used as an effective support to decrease the negative pulmonary effects of coronary artery bypass graft (CABG) surgery. However, it is unknown whether CPAP can positively influence patients undergoing CABG during exercise. This study evaluated the effectiveness of CPAP on the first day of ambulation after CABG in patients undergoing inpatient cardiac rehabilitation (CR).

METHODS

Fifty-four patients after CABG surgery were randomly assigned to receive either inpatient CR and CPAP (CPG) or standard CR without CPAP (CG). Cardiac rehabilitation included walking and CPAP pressures were set between 10 to 12 cmH2O. Participants were assessed on the first day of walking at rest and during walking. Outcome measures included breathing pattern variables, exercise time in seconds (ETs), dyspnea/leg effort ratings, and peripheral oxygen saturation (SpO2).

RESULTS

Twenty-seven patients (13 CPG vs 14 CG) completed the study. Compared with walking without noninvasive ventilation assistance, CPAP increased ETs by 43.4 seconds (P = .040) during walking, promoted better thoracoabdominal coordination, increased ventilation during walking by 12.5 L/min (P = .001), increased SpO2 values at the end of walking by 2.6% (P = .016), and reduced dyspnea ratings by 1 point (P = .008).

CONCLUSIONS

Continuous positive airway pressure can positively influence exercise tolerance, ventilatory function, and breathing pattern in response to a single bout of exercise after CABG.

摘要

目的

持续气道正压通气(CPAP)已被用作一种有效的支持手段,以减轻冠状动脉旁路移植术(CABG)手术对肺部的不良影响。然而,CPAP是否能对CABG手术患者运动期间产生积极影响尚不清楚。本研究评估了CPAP对接受住院心脏康复(CR)的CABG手术患者术后第一天行走时的有效性。

方法

54例CABG手术后患者被随机分配接受住院CR和CPAP(CPG组)或不接受CPAP的标准CR(CG组)。心脏康复包括步行,CPAP压力设定在10至12 cmH2O之间。在步行的第一天,对参与者在休息时和步行期间进行评估。观察指标包括呼吸模式变量、以秒为单位的运动时间(ETs)、呼吸困难/腿部用力评分以及外周血氧饱和度(SpO2)。

结果

27例患者(13例CPG组 vs 14例CG组)完成了研究。与无无创通气辅助的步行相比,CPAP使步行期间的ETs增加了43.4秒(P = .040),促进了更好的胸腹协调性,使步行期间的通气量增加了12.5 L/min(P = .001),使步行结束时的SpO2值增加了2.6%(P = .016),并使呼吸困难评分降低了1分(P = .008)。

结论

持续气道正压通气可对CABG术后单次运动后的运动耐力、通气功能和呼吸模式产生积极影响。

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