Çakir-Özkan Nilüfer, Bereket Cihan, Arici Nursel, Elmali Muzaffer, Şener Ismail, Bekar Esengül
*Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ondokuz Mayis University, Samsun †Department of Orthodontics, Faculty of Dentistry, Biruni University, Istanbul ‡Department of Radiology, Faculty of Medicine, Ondokuz Mayis University §Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Ondokuz Mayis University, Samsun, Turkey.
J Craniofac Surg. 2015 Oct;26(7):e595-9. doi: 10.1097/SCS.0000000000002046.
The aim of this study was to evaluate the effect of low level laser therapy (LLLT) on bone mineral density by using high-resolution computerized tomography (HR-CT) and stereology in patients subjected to mandibular midline distraction.
Nine patients between the ages of 13 and 16 years with mandibular transverse deficiency (>5 mm) were evaluated. Mandibular midline distraction osteogenesis was performed for all the patients. The patients were divided into 2 groups: the control group (n = 4) and the laser group (n = 5). GaAlAs, 830 nm wavelength, power of 40 mW, energy of 8.4 J/cm2 dose per spot, was directly applied from 2 points on the mandibular midline. The laser was applied in 8 treatment sessions at 48-hour intervals. Bone mineral density and volume of the newly formed bone were analyzed using HR-CT and stereological methods.
A higher bone mineral density rate was found in the laser group (P < 0.05). A higher newly formed immature bone rate was found in the control group (P < 0.001). These findings suggest that more mature bone may also have a greater mineral organization than that of immature newly formed bone, which is shown by HR-CT and stereological results.
The retention period can be shortened and mineralization may be increased by using LLLT in mandibular distraction osteogenesis.
本研究旨在通过高分辨率计算机断层扫描（HR-CT）和体视学方法，评估低强度激光治疗（LLLT）对下颌中线牵张成骨患者骨密度的影响。
对9例年龄在13至16岁之间、下颌横向发育不足（>5mm）的患者进行评估。所有患者均接受下颌中线牵张成骨术。将患者分为2组：对照组（n = 4）和激光组（n = 5）。从下颌中线的2个点直接施加波长830nm、功率40mW、每点能量剂量8.4J/cm²的GaAlAs激光。每隔48小时进行8次激光治疗。使用HR-CT和体视学方法分析新形成骨的骨密度和体积。
激光组的骨密度率更高（P < 0.05）。对照组新形成的未成熟骨率更高（P < 0.001）。这些发现表明，通过HR-CT和体视学结果显示，成熟骨可能比未成熟的新形成骨具有更致密的矿物质结构。
在下颌牵张成骨术中使用LLLT可缩短愈合期并增加矿化程度。
