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奥地利高血压的长期流行趋势:肥胖与社会人口统计学的影响

Prevalent Long-Term Trends of Hypertension in Austria: The Impact of Obesity and Socio-Demography.

作者信息

Großschädl Franziska, Stolz Erwin, Mayerl Hannes, Rásky Éva, Freidl Wolfgang, Stronegger Willibald J

机构信息

Medical University of Graz, Institute of Nursing Science, Billrothgasse 6, 8010, Graz, Austria.

Medical University of Graz, Institute of Social Medicine and Epidemiology, Universitätsstraße 6/I, 8010, Graz, Austria.

出版信息

PLoS One. 2015 Oct 15;10(10):e0140461. doi: 10.1371/journal.pone.0140461. eCollection 2015.

Abstract

BACKGROUND

Globally there are only less long-term-studies on hypertension available to provide reliable estimates and identify risk groups. This study aims to analyse the prevalence and long-term-trend of hypertension in Austria, recognize affected subpopulations and investigate social inequalities.

METHODS

This representative population-based study is based on self-reported data of adults (mean age: 47.7 ± 17.5; n = 178,818) that were taken from five health surveys between 1973 and 2007. An adjustment of self-reported BMI was performed based on a preliminary validation study. Absolute changes (AC) and aetiologic fractions (AF) were calculated from logistic regressions in order to measure trends. To quantify the extent of social inequality, a relative index of inequality (RII) was computed.

RESULTS

During the study period the age-standardized hypertension prevalence increased from 1.0% to 18.8%, with a considerable rise from 1991 onwards. There was a positive trend in all subpopulations, with the highest AC among obese women (+50.2%) and obese subjects aged 75 years and older (+54.4%), whereas the highest risk was observed among the youngest obese adults (AF: 99.4%). The RII for hypertension was higher for women than men, but in general unstable during the investigation period.

CONCLUSIONS

Obesity and older age are significant factors for increased morbidity of hypertension. The most undesirable trends occurred in obese women and obese subjects aged 75 years and older. These risk groups should be given special attention when planning hypertension prevention programs. The high increase in the prevalence of hypertension is due to different aspects, e.g. a demographic change and a change in the definition of hypertension. These findings help to understand why hypertension is becoming more common in the Austrian population.

摘要

背景

全球范围内,关于高血压的长期研究较少,难以提供可靠的评估并识别风险群体。本研究旨在分析奥地利高血压的患病率及长期趋势,识别受影响的亚人群,并调查社会不平等情况。

方法

这项基于人群的代表性研究基于1973年至2007年间五项健康调查中成年人的自我报告数据(平均年龄:47.7±17.5;n=178,818)。根据一项初步验证研究对自我报告的体重指数进行了调整。通过逻辑回归计算绝对变化(AC)和病因分数(AF)以衡量趋势。为了量化社会不平等程度,计算了不平等相对指数(RII)。

结果

在研究期间,年龄标准化高血压患病率从1.0%升至18.8%,1991年起显著上升。所有亚人群均呈上升趋势,肥胖女性(+50.2%)和75岁及以上肥胖者(+54.4%)的AC最高,而最年轻的肥胖成年人风险最高(AF:99.4%)。高血压的RII女性高于男性,但在调查期间总体不稳定。

结论

肥胖和高龄是高血压发病率增加的重要因素。最不利的趋势出现在肥胖女性和75岁及以上肥胖者中。在规划高血压预防项目时,应特别关注这些风险群体。高血压患病率的大幅上升是由不同因素导致的,例如人口结构变化和高血压定义的改变。这些发现有助于理解为何高血压在奥地利人群中变得更为常见。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05f0/4607455/c6d2bae1eaa3/pone.0140461.g001.jpg

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