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在大量水存在的情况下,使用波长为532纳米的脉冲皮秒激光对骨组织进行激光切割。

Laser cutting of bone tissue under bulk water with a pulsed ps-laser at 532 nm.

作者信息

Tulea Cristian-Alexander, Caron Jan, Gehlich Nils, Lenenbach Achim, Noll Reinhard, Loosen Peter

机构信息

Fraunhofer Institute for Laser Technology ILT, Steinbachstraße 15, Aachen 52074, Germany.

Fraunhofer Institute for Laser Technology ILT, Steinbachstraße 15, Aachen 52074, GermanybRWTH Aachen University, Chair for Technology of Optical Systems, Steinbachstraße 15, Aachen 52074, Germany.

出版信息

J Biomed Opt. 2015 Oct;20(10):105007. doi: 10.1117/1.JBO.20.10.105007.

Abstract

Hard-tissue ablation was already investigated for a broad variety of pulsed laser systems, which cover almost the entire range of available wavelengths and pulse parameters. Most effective in hard-tissue ablation are Er:YAG and CO2 lasers, both utilizing the effect of absorption of infrared wavelengths by water and so-called explosive vaporization, when a thin water film or water–air spray is supplied. The typical flow rates and the water layer thicknesses are too low for surgical applications where bleeding occurs and wound flushing is necessary. We studied a 20 W ps-laser with 532 nm wavelength and a pulse energy of 1 mJ to effectively ablate bones that are submerged 14 mm under water. For these laser parameters, the plasma-mediated ablation mechanism is dominant. Simulations based on the blow-off model predict the cut depth and cross-sectional shape of the incision. The model is modified considering the cross section of the Gaussian beam, the incident angle, and reflections. The ablation rate amounts to 0.2  mm3/s, corresponding to an increase by at least 50% of the highest values published so far for ultrashort laser ablation of hard tissue.

摘要

针对多种脉冲激光系统已经开展了硬组织消融研究,这些系统几乎涵盖了所有可用的波长范围和脉冲参数。在硬组织消融方面最有效的是铒钇铝石榴石(Er:YAG)激光和二氧化碳(CO2)激光,二者均利用了水对红外波长的吸收效应以及所谓的爆炸式汽化,即在提供薄水膜或水 - 空气喷雾时发生的汽化。对于会出现出血且需要冲洗伤口的外科手术应用而言,典型的流速和水层厚度过低。我们研究了一台波长为532 nm、脉冲能量为1 mJ的20 W脉冲激光,以有效消融水下14 mm深处的骨头。对于这些激光参数,等离子体介导的消融机制占主导。基于吹脱模型的模拟可预测切口的切割深度和横截面形状。该模型在考虑高斯光束的横截面、入射角和反射的情况下进行了修正。消融速率为0.2立方毫米/秒,相较于迄今发表的关于硬组织超短激光消融的最高值,至少提高了50%。

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