Guthrie S K, Lane E A, Linnoila M
College of Pharmacy, University of Michigan, Ann Arbor 48109-1065.
Alcohol Clin Exp Res. 1989 Feb;13(1):66-8. doi: 10.1111/j.1530-0277.1989.tb00285.x.
No association between acetylation phenotype and alcoholism was discovered. Fifty-four percent of both the alcoholic patients and healthy volunteers were rapid acetylators. Acetylation phenotyping is not helpful to the investigation of the genetics of alcoholism.
未发现乙酰化表型与酒精中毒之间存在关联。酒精中毒患者和健康志愿者中均有54%为快速乙酰化者。乙酰化表型分析对酒精中毒遗传学研究并无帮助。