Tokmak A, Guzel A I, Erkilinc S, Yesilyurt H, Zergeroglu S, Erkaya S, Yılmaz N
a Department of Obstetrics and Gynaecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
b Department of Pathology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
J Obstet Gynaecol. 2016;36(3):289-92. doi: 10.3109/01443615.2015.1085843. Epub 2015 Oct 15.
We aimed to evaluate the risk factors for recurrence of surgically managed ovarian mature cystic teratoma (MCT). A total of 178 women with MCT managed surgically at our clinic were included in this retrospective study. The cases were followed for a minimum of 34 months. Risk factors recorded were age, gravidity, diameter of MCT, tumour markers, bilaterality, operation time and recurrence time. One hundred forty-one women (79.2%) underwent laparoscopy and the other thirty-seven patients (20.8%) underwent laparotomy. The mean age of patients with cyst recurrence was significantly lower than that of patients without recurrence (p = 0.02). There was a significantly lower median gravidity and parity in this group. The capacity of younger age, lower gravidity and parity in predicting the recurrence of ovarian MCT was analysed using receiver operating characteristic curve analysis. The cut-off value of age, number of gravidity and parity was 26, 1 and 0, respectively. In conclusion, younger age and lower gravidity and parity were predictive of recurrence due to a more conservative approach in young and nulliparous patients. Therefore, we suggest regular follow-up visits during the postoperative period, especially for younger patients and those with lower numbers of gravidity and parity.
我们旨在评估手术治疗卵巢成熟性囊性畸胎瘤（MCT）复发的危险因素。本回顾性研究纳入了在我们诊所接受手术治疗的178例MCT女性患者。对这些病例进行了至少34个月的随访。记录的危险因素包括年龄、妊娠次数、MCT直径、肿瘤标志物、双侧性、手术时间和复发时间。141例女性（79.2%）接受了腹腔镜检查，另外37例患者（20.8%）接受了剖腹手术。囊肿复发患者的平均年龄显著低于未复发患者（p = 0.02）。该组患者的妊娠次数和产次中位数显著较低。使用受试者工作特征曲线分析来分析年龄较小、妊娠次数和产次较低对预测卵巢MCT复发的能力。年龄、妊娠次数和产次的截断值分别为26岁、1次和0次。总之，年龄较小、妊娠次数和产次较低预示着复发，这是由于年轻和未生育患者采取了更保守的治疗方法。因此，我们建议术后定期随访，尤其是对于年轻患者以及妊娠次数和产次较少的患者。
