Lubrano Ennio, Perrotta Fabio Massimo, Kavanaugh Arthur
Academic Rheumatology Unit, Department of Medicine and Health Science "Vincenzo Tiberio", University of Molise, Italy.
Division of Rheumatology, Allergy, and Immunology Center for Innovative Therapy (CIT), University of California, San Diego, La Jolla, CA, USA.
Clin Exp Rheumatol. 2015 Sep-Oct;33(5 Suppl 93):S51-4. Epub 2015 Oct 15.
Psoriatic arthritis (PsA) is a complex, multisystem and potentially disabling disease with musculoskeletal and skin manifestations. In PsA, as well as in the other chronic rheumatic conditions, a state of low disease activity or remission should be the target of treatment but to reach this objective, in the assessment of PsA patients, is still an unmet need due to the heterogeneity of disease manifestations. With the introduction of anti-TNF treatment, low disease activity or remission become an achievable and suitable state that could be reached by 50%-60% of PsA patients. The aim of this paper is to briefly summarise the concept of low disease activity and remission in PsA, with particular focus on anti-TNF therapy.
银屑病关节炎（PsA）是一种复杂的多系统疾病，可能导致残疾，具有肌肉骨骼和皮肤表现。在PsA以及其他慢性风湿性疾病中，低疾病活动度或缓解状态应是治疗的目标，但由于疾病表现的异质性，在评估PsA患者时，要实现这一目标仍是一项未满足的需求。随着抗TNF治疗的引入，低疾病活动度或缓解成为一种可实现且合适的状态，50%-60%的PsA患者可以达到这种状态。本文的目的是简要总结PsA中低疾病活动度和缓解的概念，尤其关注抗TNF治疗。
