成人和青少年淋球菌感染的管理：新的关键建议。
Management of gonococcal infection among adults and youth: New key recommendations.
作者信息
Pogany Lisa, Romanowski Barbara, Robinson Joan, Gale-Rowe Margaret, Latham-Carmanico Cathy, Weir Christine, Wong Tom
机构信息
Epidemiologist in the Centre for Communicable Diseases and Infection Control at the Public Health Agency of Canada in Ottawa, Ont.
Clinical Professor of Medicine in the Faculty of Medicine and Dentistry at the University of Alberta in Edmonton.
出版信息
Can Fam Physician. 2015 Oct;61(10):869-73, e451-6.
OBJECTIVE
To provide recommendations on the management of gonococcal infection among adults and youth.
QUALITY OF EVIDENCE
Treatment recommendations in the Canadian guidelines on sexually transmitted infections are based on review of the literature, as well as the grades of recommendations and the levels of evidence quality determined by a minimum of 2 reviewers. The recommendations are peer-reviewed and require approval by the expert working group.
MAIN MESSAGE
The new key recommendations for managing gonococcal infection among adults and youth include using culture as a diagnostic tool when practical, providing treatment with combination antibiotic therapy (ceftriaxone combined with azithromycin), and promptly reporting all cases with treatment failure to public health.
CONCLUSION
Following these new key recommendations might reduce treatment failure, contribute to better surveillance of antibiotic-resistance trends in Neisseria gonorrhoeae, and contribute to the prevention of transmission of multidrug-resistant gonorrhea.
目的
为成人和青少年淋病感染的管理提供建议。
证据质量
加拿大性传播感染指南中的治疗建议基于文献综述，以及至少两名评审员确定的建议等级和证据质量水平。这些建议经过同行评审，并需得到专家工作组的批准。
主要信息
成人和青少年淋病感染管理的新关键建议包括在可行时使用培养作为诊断工具，采用联合抗生素疗法（头孢曲松联合阿奇霉素）进行治疗，并将所有治疗失败的病例及时报告给公共卫生部门。
结论
遵循这些新的关键建议可能会减少治疗失败，有助于更好地监测淋病奈瑟菌的抗生素耐药趋势，并有助于预防多重耐药淋病的传播。
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